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Structural Correlates of Antibodies Associated with Acute Reversal of Amyloid beta-related Behavioral Deficits in a Mouse Model of Alzheimer DiseaseBasi, G.S. and others.Journal of Biological Chemistry, 2010, 285, 3417-3427
Neutralizing and Non-neutralizing Monoclonal Antibodies Against Dengue Virus E Protein Dervied from a Naturally Infected Patient.Schieffelin, J.S.; Costin, J. M.; Nicholson, C. O.; Orgeron, N. M.; Fontaine, K. A.; Isern, S.; Michael, S. F.; Robinson, J. E.Virology Journal, 2010, 7, 28-38
Reconstitution of a Frizzled8-Wnt3a-LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.Bourhis, E.; Tam, C.; Franke, Y.; Bazan, J. F.; Ernst, J.; Hwang, J.; Costa, M.; Cochran, A. G.; Hannoush, R. N.Journal of Biological Chemistry, 2010, 285 (12), 9172-9179
Molecular Mechanism of the Syanptotagmin-SNARE Interaction in Ca2+-Triggered Vesicle Fusion.Vrljic, M.; Strop, P.; Ernst, J. A.; Sutton, R. B.; Chu, S.; Brunger, A. T.Nature Structural and Molecular Biology, 2010, 17, 325-331
Recombinant Respiratory Syncytial Virus F Protein Expression is Hindered by Inefficient Nuclear Export and mRNA ProcessingHuang, K.; Lawlor, H.; Tang, R.; MacGill, R. S.; Ulbrandt, N. D.; Wu, H.Virus Genes, 2010, 40 (2), 212-221
Human Framework Adaptation of a Mouse Anti-Human IL-13 AntibodyFransson, J. and others.Journal of Molecular Biology, 2010, 398 (2), 214-231
Grading the Commercial Optical Biosensor Literature - Class of 2008: The Mighty BindersRich, R. L.; Myszka, D. G.Journal of Molecular Recognition, 2010, 23, 1-64
Binding Rate Screen - A High-Throughput Assay in Soluble Lysate for Prioritizing Protein Expression ConstructsTian-Yu, J.; Licht, S.; Pardee, G.; Bhat, A.; Cao, Y.; Gao, W.; Sangalang, E.; Zaror, I.Analytical Biochemistry, 2010, 399 (2), 276-283
Design and Generation of Human de Novo pIX Phage Display Libraries.Tsui, P. and others.Johnson & Johnson, Inc., United States Patent Application 20100021477
N-Glycans and Uses Thereof.Liu, C.; Xiang, J.; Yan, S.; Wang, P.; Tai, W. C.Eureka Therapeutics, Inc., United State Patent Application 20100081172
Modified Host Cells and Uses Thereof.Liu, C.; Xiang, J.; Yan, S.; Wang, P.; Tai, W. C.Eureka Therapeutics Inc., United States Patent Application 20100081195
Methods for Generating Host CellsLiu, C.; Xiang, J.; Yan, S.; Wang, P.; Tai, W. C.Eureka Therapeutics Inc., United States Patent Application 20100081150
Modified Glycoproteins and Uses Thereof.Liu, C.; Xiang, J.; Yan, S.; Wang, P.; Tai, W. C.Eureka Therapeutics Inc., United States Patent Application 20100081794
Immobilization and Application of Antigenic Carbohydrates to Detec Infective MicroorganismsBergwerff, A. A. and others.United States Patent Application 20100062416
Methods of Therapeutic Treatment of EyesArchambeau, G. J.; Wood, A. B.; Watson, R. L.Revalesio Corporation, United States Patent Application 20100028442
The Structure of SHH in Complex with HHIP Reveals a Recognition Role for the Shh Pseudo Active Site in SignalingBosanac, I.; Maun, H.R.; Scales, S.J.; Wen, X.; Lingel, A.; Bazan, J.F.; de Sauvage, F.J.; Hymowitz, S.G.; Lazarus, R.A.Nature Structural & Molecular Biology, 2009, 16 (7), 691 - 698.
Label-free Detection of Biomolecular Interactions Using BioLayer Interferometry for Kinetic Characterization.Concepcion, J and othersCombinatorial Chemistry and High Throughput Screening, 2009, 12, 791 - 800
Poxvirus Proteomics and Virus-Host Protein InteractionsVan Vliet, K.; Mohamed, M. R.; Zhang, L.; Villa, N. Y.; Werden, S. J.; Liu, J.; McFadden, G.Microbiology and Molecular Biology Reviews, 2009, 73 (4), 730-749
Structural Basis for Parathyroid Hormone-Related Protein Binding to the Parathyroid Hormone Receptor and Design of Conformation-Selective PeptidesPioszak, A. A.; Parker, N. R.; Gardella, T. J.; Xu, H. E.Journal of Biological Chemistry, 2009, 284, 28382-28391
Structure of IL-33 and Its Interaction with the ST2 and IL-1RAcP Receptors - Insight into Heterotrimeric IL-1 Signaling ComplexesLingel, A.; Weiss, T. M.; Niebuhr, M.; Pan, B.; Appleton, B. A.; Wiesmann, C.; Bazan, J. F.; Fairbrother, W. J.Structure, 2009, 17 (10), 1398-1410
A Predictive High-Throughput Scale-Down Model of Monoclonal Antibody Production in CHO CellsLegmann, R.; Schreyer, H. B.; Combs, R. G.; McCormick, E. L.; Russon, A. P.; Rodgers, S. T.Biotechnology and Bioengineering, 2009, 104 (6), 1107-1120
Fluidics-Free Molecular Interactions Analysis.Witte, K.Genetic and Engineering News, 2009, July 1, 29 (13)
Who Needs Labels? Macromolecular Interaction Sans Labels.Perkel, J. M.Science, 2009, Sep. 19, 1561
Direct Optical Detection in Fragment-Based Screening.Proll, F.; Fechner, P.; Proll, G.Analytical and Bioanalytical Chemistry, 2009, 393, 1557 - 1562
A Global Benchmark Study Using Affinity-based Biosensors.Rich, R.L. and othersAnalytical Biochemistry, 2009, 386 (2), 194-216
Human Antibodies to Human Delta Like Ligand 4.Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.Regeneron Pharmaceuticals Inc., United States Patent 7,534,868
Antibodies to the PcrV Antigen of Pseudomonas Aeruginosa.Bebbington, C. R.; Luehrsen, K.; Yarranton, G. T.; Baer, M.KaloBios Pharmaceuticals Inc., United States Patent Application 20090191186
Universal Fibronectin Type III Binding-Domain Libraries.Cappuccilli, G.; Crea, R.; Shen, R.; Hokanson, C. A.; Kirk, P. B.; Liston, D. R.ProtElix, Inc., United States Patent Application 20090176654
Human Antibodies to Human Delta Like Ligand 4.Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.Regeneron Pharmaceuticals Inc., United States Patent Application 20090142354
Compositions that Bind Multiple Epitopes of IGF-1R.Glaser, S.; Demarest, S.; Miller, B. R.; Hariharan, K.; Ho, S.; Dong, J.; Lugovskoy, A. A.United States Patent Application 20090130105
Novel Rabbit Antibody Humanization Methods and Humanized Rabbit Antibodies.Kovacevich, B. R.; Latham, J.Alder Biopharmaceuticals Inc., United States Patent Application 20090104187
Label-free, Real-time Detection System for Molecular Interaction Analysis.Lotze, M. T.The University of Pittsburgh, United States Patent Application 20090147264
High Affinity Human Antibodies to Human Nerve Growth Factor.MacDonald, L.; Torres, R.; Morra, M. R.; Martin, J. H.; Reinhardt, J. C.Regeneron Pharmaceuticals Inc., United States Patent Application 20090041717
Antibodies to IL-6 and Use Thereof.Garcia-Martinez, L.; Jensen, A. E. C.; Olson, K.; Dutzar, B.; Ojala, E.; Kovacevich, B.; Latham, J.; Smith, J. T. L.Alder Biopharmaceuticals Inc., United States Patent Application 20090028784
Antibodies to TNF Alpha and Use Thereof.Olson, K.; Dutzar, B.; Jensen, A. E. C.; Garcia-Martinez, L.; Ojala, E.; Latham, J.Alder Biopharmaceuticals Inc., United States Patent Application 20090022659
Human Antibodies to Human Delta-like Ligand 4.Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.Regeneron Pharmaceuticals, Inc., United States Patent Application 20090017035
Exploring Blocking Assays Using Octet, ProteOn, and Biacore Biosensors.Abdiche, Y. N.; Malashock, D. S.; Pinkerton, A; Pons, J.Analytical Biochemistry, 2009, 386(2), 172-180
Human Antibodies to Human Delta-like Ligand 4.Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.Regeneron Pharmaceuticals, Inc., United States Patent 7,488,806
A Rapid Method for Determining Dynamic Binding Capacity of Resins for the Purification of Proteins.Do, T.; Ho, F.; Heidecker, B.; Witte, K.; Chang, L.; Lerner, L.Protein Expression and Purification, 2008, 60, 147-150
The Surface Protein TIGIT Suppresses T Cell Activation by Promoting the Generation of Mature Immunoregulatory Dendritic Cells.Yu, X.; Harden, K.; Gonzalez, L. C.; Francesco, M.; Chiang, E.; Irving, B.; Tom, I.; Ivelja, S.; Refino, C. J.; Clark, H.; Eaton, D.; Grogan, J. L.Nature Immunology, 2008, 10, 48-57
Advantages and Application of Label-free Detection Assays in Drug Screening.Cunningham, B. T.; Laing, L. G.Expert Opinion on Drug Discovery, 2008, 3(8), 891-901
Humaneered Anti-factor B Antibody.Emlen, W.; Holers, V. M.; Flynn, P.Taligen Therapeutics, Inc., United States Patent Application 20080299114
Antibodies to Lymphotoxin-Alpha.Adams, C. W.; Grogan, J. L.; Gurney, A. L.; McCutcheon, K.Genentech Inc., WIPO Patent Application No. WO2008063776.
Human Antibodies to Human Delta-like Ligand 4.Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.Regeneron Pharmaceuticals, Inc., United States Patent Application 20080181899
High Affinity Human Antibodies to Human IL-4 Receptor.Stevens, S.; Huang, T. T.; Martin, J. H.; Farihurst, J. L.; Rafique, A.; Torres, M.; Pobursky, K. J.; Leidich, R. W.; Windsor, J. A.; Mikulka, W. R.; Ahrens, D. M.; Shi, E.; Papadopoulos, N. J.Regeneron Pharmaceuticals, Inc., United States Patent Application 20080160035
Probing the Binding Mechanism and Affinity of Tanezumab, a Recombinant Humanized Anti-NGF Monoclonal Antibody, Using a Repertoire of Biosensors.Abdiche, Y. N.; Malashock, D. S.; Pons, J.Protein Science, 2008, 17(8), 1326-1335
Determining Kinetics and Affinities of Protein Interactions Using a Parallel Real-time Label-free Biosensor, the Octet.Abdiche, Y.N.; Malashock, D. S.; Pinkerton, A; Pons, J.Analytical Biochemistry, 2008, 377(2), 209-217
WNT Antagonists and Their Use in the Diagnosis and Treatment of WNT-mediated Disorders.Ernest, J. A.; Polakis, P.; Rubinfeld, B.; Dealmeida, V. I.Genentech, Inc., United States Patent Application 20080299136
Detecting DNA: Getting and Begetting Cancer.Farkas, A. M.; Kilgore, T. M.; Lotze, M. T.Current Opinion in Investigational Drugs, 2007, 8, 981-986
Culture Method for Obtaining a Clonal Population of Antigen-specific B Cells.Jensen, A. E. C.; Garcia, L.; Ojala, E.; Latham, J.Alder Biopharmaceuticals, Inc., United States Patent Application 20070269868
Label-free Optical Biosensors in Drug Discovery.Fang, Y.Trends in Biopharmaceutical Industry, 2007, 3, 34-38
Higher-throughput, label-free, real-time molecular interaction analysis.Rich, R. L.; Myszka, D. G.Analytical Biochemistry, 2007, 361, 1-6
Optical Biosensors: Where Next and How Soon?Cooper, M. A.Drug Discovery Today, 2006, 11 (23-24), 1061-1067
Current Biosensor Technologies in Drug Discovery.Cooper, M. A.Drug Discovery World, 2006, 68-82
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