References to Fortebio's Products in Published Literature

2011

A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses
Ekiert, D. C. et. al.
Science, 2011, July 7, Epub ahead of print

Detection of Deoxynivalenol using Biolayer Interferometry
Maragos, C. M.
Mycotoxin Research, 2011, 27, 157-165

Biosensor-based Small Molecule Fragment Screening with Biolayer Interferometry
Wartchow, C. A.; Podlaski, F.; Li, S.; Rowan, K.; Zhang, X.; Mark, D.; Huang, K-S.
Journal of Computer-aided Molecular Design, DOI: 10.1007/s10822-011-9439-8

Soluble periplasmic production of human granulocyte colony-stimulating factor (G-CSF) in Pseudomonas fluorescens
Jin, H.; Cantin, G. T.; Maki, S.; Chew, L. C.; Resnick, S. M.; Ngai, J.; Retallack, D. M.
Protein Expression and Purification, 2011, 78 (1), 69-77

Chaperone Activity of alpha B-Crystallin Is Responsible for Its Incorrect Assignment as an Autoantigen in Multiple Sclerosis
Rothbard, J. B.; Zhao, X.; Sharpe, O.; Strohman, M. J.; Kurnellas, M.; Melins, E. D.; Robinson, W. H.; Steinman, L.
The Journal of Immunology, 2011, 186 (7), 4263-4268

Structural and Biophysical Analysis of Bst-2/Tetherin Ectodomains Reveals an Evolutionary Conserved Design to Inhibit Virus Release
Swiecki, M.; Scheaffer, S. M.; Allaire, M.; Fremont, D. H.; Colonna, M.; Brett, T. J.
The Journal of Biological Chemistry, 2011, 286, 2987-2997

Role of Iron and Sodium Citrate in Animal Protein-Free CHO Cell Culture Medium on Cell Growth and Monoclonal Antibody Production
Bai, Y.; Wu, C.; Zhao, J.; Liu, Y-H.; Ding, W.; Ling, W. L. W.
Biotechnology Progress, 2011, 27 (1), 209-219

Chronic Intranasal Treatment with an Anti-Aâ30-42 scfv Antibody Ameliorates Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease
Cattepoel, S.: Hanenberg,M.; Kulic, L.; Nitsch, R. M.
PLoS ONE, 2011, 6 (4), e18296

Exploiting Nucleotide Composition to Engineer Promoters
Grabherr, M. G. et. al.
PLoS ONE, 2011, 6 (5), e20136

The Peroxisomal Targeting Signal 1 in Sterol Carrier Protein 2 is Autonomous and Essential for Receptor Recognition
Williams, C. P. et. al.
BMC Biochemistry, 2011, 12:12

Comparison of an Antibody Capture and a Cell Capture Ligand-Binding Assay to Quantify a Monoclonal Therapeutic in Serum
Spriggs, F.; Aggarwal, P.; Deng, S.; Soderstrom, C.; Donovan, C.
Bioanalysis, 2011, 3 (6), 605-611

Mutations in the G-H Loop Region of Ephrin-B2 can Enhance Nipah Virus Binding and Infection
Yuan, J.; Marsh, G.; Khetawat, D.; Broder, C.; Wang, L.; Shi, Z.
Journal of General Virology, 2011, Vir.0.033787-0

TMEFF2 is a PDGF-AA Binding Protein with Methylation-Associated Gene Silencing in Multiple Cancer Types Including Glioma
Lin, K. et. al.
PLoS ONE, 2011, 6 (4), e18608

Challenges in Developing Bioanalytical Assays for Characterization of Antibody–Drug Conjugates
Stephan, J. P. ; Kozak, K. R.; Wong, W. T.
Bioanalysis, 2011, 3 (6), 677-700

An Insertion Mutation That Distorts Antibody Binding Site Architecture Enhances Function of a Human Antibody
Krause, J. C.; Ekiert, D. C.; Tumpey, T. M.; Smith, P. B.; Wilson, I. A.; Crowe Jr., J. E.
mBio, 2011, 2 (1), e00345-10

Lysine Acetylation is a Widespread Protein Modification for Diverse Proteins in Arabidopsis
Wu, X. et. al.
Plant Physiology, 2011, 155 (4), 1769–1778

Robo4 Maintains Vessel Integrity And Inhibits Angiogenesis By Interacting With UNC5B
Koch, A. W. et. al.
Developmental Cell, 2011, 20 (1), 33-46

Design of a Reversible Biotin Analog and Applications in Protein Labeling, Detection, and Isolation
Ying, L.; Branchaud, B. P.
Chemical Communications, 2011, DOI: 10.1039/c1cc12738a

Divergent Activities Of Osteogenic BMP2, And Tenogenic BMP12 And BMP13 Independent Of Receptor Binding Affinities
Berasi, S. P. et. al.
Growth Factors, 2011, 29 (4), 128-139

Label Free Inhibitor Screening of Hepatitis C Virus (HCV) NS5B Viral Protein Using RNA Oligonucleotide
Roh, C.; Kim, S. E.; Jo, S.
Sensors, 2011, 11, 6685-6696

Development and Characterization of APRIL Antagonistic Monoclonal Antibodies for Treatment of B-Cell Lymphomas
Guadagnoli, M. et. al.
Blood, 2011, 117, 6856-6865

Role of Iron and Sodium Citrate in Animal Protein-Free CHO Cell Culture Medium on Cell Growth and Monoclonal Antibody Production
Bai, Y. et. al.
Biotechnology Progress, 2011, 27 (1), 209-219

Integrin Binding Human Antibody Constant Domains – Probing the C-terminal Structural Loops for Grafting the RGD Motif
Traxlmayr, M. W. et. al.
Journal of Biotechnology, 2011, doi:10.1016/j.jbiotec.2011.06.042

Review of Transducer Principles for Label-Free Biomolecular Interaction Analysis
Nirschl, M.; Reuter, F.; Voros, J.
Biosensors, 2011, 1, 70-92

2010

Cytokine Binding by Polysaccharide-Antibody Conjugates
Sun, L. T.; Buchholz, K. S.; Lotze, M. T.; Washburn, N. R.
Molecular Pharmaceutics, 2010, 7 (5), 1769 – 1777

Generation of Stable Cell Clones Expressing Mixtures of Human Antibodies
De Kruif, J. and others.
Biotechnology and Bioengineering, 2010, 106 (5), 741 – 750

Humanization Strategies for an Anti-idiotypic Antibody Mimicking HIV-1 gp41
Mader, A.; Kunert, R.
Protein Engineering, Design & Selection, 2010, 23 (12), 947 – 954

Gambogic Acid Inhibits Hsp90 and Deregulates TNF-alpha/NF-kappaB in HeLa Cells
Zhang, L.; Yi, Y.; Chen, J.; Sun, Y.; Guo, Q.; Zheng, Z.; Song, S.
Biochemical and Biophysical Research Communications, 2010, 403, 282 – 287

Autophosphorylation of Tyr-610 in the Receptor Kinase BAK1 Plays a Role in Brassinosteroid Signaling and Basal Defense Gene Expression
Oh, M. –H.; Wang, X.; Wu, X.; Zhao, Y.; Clouse, S. D.; Huber, S. C.
Proceedings of the National Academy of Sciences, 2010, Sep. 27, doi: 10.1073/pnas.0915064107

Allosteric Peptide Activators of Pro-Hepatocyte Growth Factor Stimulate Met Signaling
Landgraf, K. E. and others.
Journal of Biological Chemistry, 2010, 285, 40362 – 40372

Specificity for Human Hemoglobin Enhances Staphylococcus aureus Infection
Pischany, G.; McCoy, A. L.; Torres, V. J.; Krause, J. C.; Crowe, Jr., J. E.; Fabry, M. E.; Skaar, E. P.
Cell Host & Microbe, 2010, 8, 544 – 550

Development and Evaluation of Monoclonal Antibodies against Phosphatidylethanolamine Binding Protein 1 in Pancreatic Cancer Patients
Wang, X. and others.
Journal of Immunological Methods, 2010, 362, 151 – 160

Detection of Low-Affinity Anti-Drug Antibodies and Improved Drug Tolerance in Immunogenicity Testing by Octet Biolayer Interferometry
Li, J.; Schantz, A.; Schwegler, M.; Shankar, G.
Journal of Pharmaceutical and Biomedical Analysis, 2011, 54 (2), 286 - 294

Wnt Isoform-Specific Interactions with Coreceptor Specify Inhibition or Potentiation of Signaling by LRP6 Antibodies
Gong, Y.; Bourhis, E. and others.
PLoS ONE, 2010, 5 (9), e12682

High-throughput Screening and Selection of Yeast Cell Lines Expressing Monoclonal Antibodies
Barnard, G. C. and others.
Journal of Industrial Microbiology and Biotechnology, 2010, 37, 961-971

Structural Bases for the Interaction of Frataxin with the Central Components of Iron-Sulphur Cluster Assembly
Prischi, F.; Konarev, P. V.; Iannuzzi, C.; Pastore, C.; Adinolfi, S.; Martin, S. R.; Svergun, D. I.; Pastore, A.
Nature Communications, 2010, 1:95, doi: 10.1038/ncomms1097.

Design Principles for Cytokine-Neutralizing Gels: Cross-linking Effects
Sun, L. T.; Bencherif, S. A.; Gilbert, T. W.; Lotze, M. T.; Washburn, N. R.
Acta Biomaterialia, 2010, 6 (12), 4708 - 4715

Optical Biosensing: Kinetics of Protein A-IgG Binding Using Biolayer Interferometry
Wilson, J. L.; Scott, I. M.; McMurry, J. L.
Biochemistry and Molecular Biology Education, 2010, 38 (6), 400 - 407

Flexible Label-free Quantitative Assay for Antibodies to Influenza Virus Hemagglutinins
Carney, P. J.; Lipatov, A. S.; Monto, A. S.; Donis, R. O.; Stevens, J.
Clinical and Vaccine Immunology, 2010, 17, 1407-1416

GP369, an FGFR2-IIIb Specific Antibody, Exhibits Potent Antitumor Activity against Human Cancers Driven by Activated FGFR2 Signaling
Bai, A., and others.
Cancer Research, 2010, 70 (19), 7630 - 7639

Direct Transactivator-Transcription Factor IID (TFIID) Contacts Drive Yeast Ribosomal Protein Gene Transcription
Layer, J. H.; Miller, S. G.; Weil, P. A.
Journal of Biological Chemistry, 2010, 285 (20), 15489-15499

Kinetic Characterization of Salmonella FliK-FlhB Interactions Demonstrates Complexity of the Type III Secretion Substrate-Specificity Switch
Morris, D. P.; Roush, E. D.; Thompson, J. W.; Moseley, M. A.; Murphy, J. W.; McMurry, J. L.
Biochemistry, 2010, 49 (30), 6386 – 6393

Structural Optimization and De Novo Design of Dengue Virus Entry Inhibitory Peptides
Costin, J. M.; Jenwitheesuk, E.; Lok, S. –M.; Hunsperger, E.; Conrads, K. A.; Fontaine, K. A.; Rees, C. R.; Rossmann, M. G.; Isern, S.; Samudrala, R.; Michael, S. F.
PLoS Neglected Tropical Diseases, 2010, 4(6): e721

A High-Throughput Purification of Monoclonal Antibodies from Glycoengineered Pichia Pastoris
Jiang, Y.; Li, F.; Button, M.; Cukan, M.; Moore, R.; Sharkey, N.; Li, H.
Protein Expression and Purification, 2010, 74 (1), 9 - 15

The Hedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-Active Site
Maun, H. R.; Wen, X.; Lingel, A.; de Sauvage, F. J.; Lazarus, R. A.; Scales, S. J.; Hymowitz, S. G.
Journal of Biological Chemistry, 2010, 285 (34), 26570-26580

A Diversity of Antibody Epitopes Can Induce Signaling Through the Erythropoietin Receptor
Lim, A. C.; Ketchem, R. R.; Borges, L.; Carabeo, T.; Carter, J.; Hoover, J. E.; Hu, Z.; Wittekind, M.; Zhou, H.; Mehlin, C.
Biochemistry, 2010, 49 (18), 3797-3804

Molecular Basis of FIR-Mediated c-myc Transciptional Control
Cukier, C. D.; Hollingworth, D.; Martin, S. R.; Kelly, G.; Diaz-Moreno, I.; Ramos, A.
Nature Structural and Molecular Biology, 2010, 17, 1058 - 1064

Surface Plasmon Resonance for Vaccine Design and Efficacy Studies: Recent Applications and Future Trends
Hearty, S.; Conroy, P. J.; Ayyar, B. V.; Byrne, B.; O’Kennedy, R.
Expert Review of Vaccines, 2010, 9 (6), 645 – 664

Unwanted Immunogenicity: Lessons Learned and Future Challenges
Wadhwa, M. and Thorpe, R.
Bioanalysis, 2010, 2 (6), 1073 – 1084

Structural Correlates of Antibodies Associated with Acute Reversal of Amyloid beta-related Behavioral Deficits in a Mouse Model of Alzheimer Disease
Basi, G.S. and others.
Journal of Biological Chemistry, 2010, 285, 3417-3427

Neutralizing and Non-neutralizing Monoclonal Antibodies Against Dengue Virus E Protein Dervied from a Naturally Infected Patient.
Schieffelin, J.S.; Costin, J. M.; Nicholson, C. O.; Orgeron, N. M.; Fontaine, K. A.; Isern, S.; Michael, S. F.; Robinson, J. E.
Virology Journal, 2010, 7, 28-38

Reconstitution of a Frizzled8-Wnt3a-LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.
Bourhis, E.; Tam, C.; Franke, Y.; Bazan, J. F.; Ernst, J.; Hwang, J.; Costa, M.; Cochran, A. G.; Hannoush, R. N.
Journal of Biological Chemistry, 2010, 285 (12), 9172-9179

Molecular Mechanism of the Synaptotagmin-SNARE Interaction in Ca2+-Triggered Vesicle Fusion.
Vrljic, M.; Strop, P.; Ernst, J. A.; Sutton, R. B.; Chu, S.; Brunger, A. T.
Nature Structural and Molecular Biology, 2010, 17, 325-331

Rapid Identification of Production Strains
Kumaraswamy, S.; Allen, J. R.
Genetic and Engineering News, 2010, June 15, 30 (12)

Recombinant Respiratory Syncytial Virus F Protein Expression is Hindered by Inefficient Nuclear Export and mRNA Processing
Huang, K.; Lawlor, H.; Tang, R.; MacGill, R. S.; Ulbrandt, N. D.; Wu, H.
Virus Genes, 2010, 40 (2), 212-221

Human Framework Adaptation of a Mouse Anti-Human IL-13 Antibody
Fransson, J. and others.
Journal of Molecular Biology, 2010, 398 (2), 214-231

Grading the Commercial Optical Biosensor Literature - Class of 2008: The Mighty Binders
Rich, R. L.; Myszka, D. G.
Journal of Molecular Recognition, 2010, 23, 1-64

Binding Rate Screen - A High-Throughput Assay in Soluble Lysate for Prioritizing Protein Expression Constructs
Tian-Yu, J.; Licht, S.; Pardee, G.; Bhat, A.; Cao, Y.; Gao, W.; Sangalang, E.; Zaror, I.
Analytical Biochemistry, 2010, 399 (2), 276-283

High Affinity Human Antibodies to Human IL-4 Receptor.
Stevens, S.; Huang, T. T. and others.
Regeneron Pharmaceuticals, Inc., United States Patent No. 7,794,717

Neutralizing Determinants of IL-17 Receptor A and Antibodies That Bind Thereto.
Tocker, J.; Mehlin, C.; Lim, A. C.
Amgen Inc., United States Patent No. 7,767,206

Polynucleotides Encoding IL-17 Receptor A Antigen Binding Properties.
Tocker, J.; Peschon, J. J.; Smothers, J. F.
Amgen Inc., Unites States Patent No. 7,786,284

Antibodies to IL-6 and User Thereof.
Garcia-Martinez, L. and others.
Alder Biopharmaceuticals Inc., United States Patent Application 20100150829

Design and Generation of Human de Novo pIX Phage Display Libraries.
Tsui, P. and others.
Johnson & Johnson, Inc., United States Patent Application 20100021477

Antibodies to IL-6 and User Thereof.
Garcia-Martinez, L. and others.
Alder Biopharmaceuticals Inc., United States Patent Application 20100129357

Antibody Producing Non-human Mammals.
Logtenberg, T.; Throsby, M.; Kramer, R. A.; Pinto, R. D.; de Kruif, C. A.; Houtzager, E.
Merus B. V., United States Patent Application 20100146647

Antagonists of IL-6 to Prevent or Treat Thrombosis
Smith, J. T. L.
Alder Biopharmaceuticals Inc., United States Patent Application 20100143294

Universal Fibronectin Type III Binding-Domain Libraries
Cappuccilli, G.; Crea, R.; Shen, R.; Hokanson, C. A.; Kirk, P. B.; Liston, D. R.
ProtElix, Inc., United States Patent Application 20100152063

N-Glycans and Uses Thereof.
Liu, C.; Xiang, J.; Yan, S.; Wang, P.; Tai, W. C.
Eureka Therapeutics, Inc., United State Patent Application 20100081172

Antagonists of IL-6 to Prevent or Treat Cachexia, Weakness, Fatigue and/or Fever
Smith, J. T. L.; Latham, J.; Litton, M. J.; Schatzman, R. C.
Alder Biopharmaceuticals Inc., United States Patent Application 20100158859

Treatment and Diagnosis of Abnormal Bone Density with an Inhibitor of the Glypican-Sclerostin Interaction
Chan, A. B.
A Chan Holding B. V., United States Patent Application 20100129378

Light Targeting Molecules and Uses Thereof
Wang, X.; Bailly, V.; Lugovskoy, A.; Farrington, G. K.; Graff, C.
Biogen Idec MA Inc., United States Patent Application 20100119511

Engineered Anti-IL-13 Antibodies, Compositions, Methods and Uses
Swanson, R. V. and others.
Johnson & Johnson, United States Patent Application 20100111959

Modified Host Cells and Uses Thereof.
Liu, C.; Xiang, J.; Yan, S.; Wang, P.; Tai, W. C.
Eureka Therapeutics Inc., United States Patent Application 20100081195

Methods for Generating Host Cells
Liu, C.; Xiang, J.; Yan, S.; Wang, P.; Tai, W. C.
Eureka Therapeutics Inc., United States Patent Application 20100081150

Modified Glycoproteins and Uses Thereof.
Liu, C.; Xiang, J.; Yan, S.; Wang, P.; Tai, W. C.
Eureka Therapeutics Inc., United States Patent Application 20100081794

Immobilization and Application of Antigenic Carbohydrates to Detect Infective Microorganisms
Bergwerff, A. A. and others.
United States Patent Application 20100062416

Methods of Therapeutic Treatment of Eyes
Archambeau, G. J.; Wood, A. B.; Watson, R. L.
Revalesio Corporation, United States Patent Application 20100028442

High Affinity Human Antibodies to Human IL-4 Receptor
Stevens, S.; Huang, T. T.; Martin, J. H.; Fairhurst, J. L.; Rafique, A.; Torres, M.; Pobursky, K. J.; Leidich, R. W.; Windsor, J. A.; Mikulka, W. R.; Ahrens, D. M.; Shi, E.; Papadopoulos, N. J.
Regeneron Pharmaceuticals, Inc., United States Patent Application 20100021476

Immobilization and Application of Antigenic Carbohydrates to Detect Infective Micro-organisms
Bergwerff, A. A.; van Eerden, E.; Nacken, P. J.; Gortemaker, B. G. M.; Wolbert, R. B. G.
Inventor Organization unknown, United States Patent Application 20100062416

Multiplex Detection of Cell Surface Receptors or Immobilized Antigens
Cen, H.
Leap Biosciences Corporation, United States Patent Application 20100062461

Antibody Producing Non-human Mammals
Houtzager, E.; Pinto, R. D.; Logtenberg, T.; Throsby, M.
Merus B. V., United States Patent Application 20100069614

Expression of Surrogate Light Chains
Horowitz, L.; Bhatt, R. R.
Sea Lane Biotechnologies, United States Patent Application 20100330676

Methods of Modulating the Proliferation and Differentiation Potential of Stem Cells and Progenitor Cells
Knoblich, J.; Schwamborn, J.
Institut Fur Molekulare Biotechnologie GMBH, United States Patent Application 20100317563

Antagonist Antibodies of Protease Activated Receptor-1 (PAR-1)
Luehrsen, K. R.
GINRF, United States Patent Application 20100330090

High Affinity Human Antibodies to Human IL-4 Receptor
Stevens, S. and others.
Regeneron Pharmaceuticals, Inc., United States Patent Application 20100291107

Antibodies to IL-6 and Use Thereof
Garcia-Martinez, L. and others.
Alder Biopharmaceuticals Inc., United States Patent Application 20100290993

Antibodies Immunoreactive with Heregulin-Coupled HER3
Keyt, B.; Kauvar, L. M. and others.
Trellis Biosciences, United States Patent Application 20100310557

Combination Antibiotic and Antibody Therapy for the Treatment of Pseudomonas Aeruginosa Infection
Baer, M. and others.
KaloBios Pharmaceuticals, Inc., United States Patent Application 20100272736

Antibodies to Human Programmed Death Receptor PD-1
Carven, G. J. and others.
Organon USA, Inc., c/o Merck, United States Patent Application 20100266617

Wnt Antagonists and their Use in the Diagnosis and Treatment of Wnt-Mediated Disorders
Ernst, J. A. and others.
Genentech, Inc., United States Patent Application 20100266593

2009

The Structure of SHH in Complex with HHIP Reveals a Recognition Role for the Shh Pseudo Active Site in Signaling
Bosanac, I.; Maun, H.R.; Scales, S.J.; Wen, X.; Lingel, A.; Bazan, J.F.; de Sauvage, F.J.; Hymowitz, S.G.; Lazarus, R.A.
Nature Structural & Molecular Biology, 2009, 16 (7), 691 - 698.

Label-free Detection of Biomolecular Interactions Using BioLayer Interferometry for Kinetic Characterization.
Concepcion, J and others
Combinatorial Chemistry and High Throughput Screening, 2009, 12, 791 - 800

Antibodies to Granulocyte-Macrophage Colony-Stimulating Factor
Bobbington, C. R.; Luehrsen, K.; Yarranton, G. T.
Kalobios Pharmaceuticals, Inc., United States Patent Application 20090274706

Poxvirus Proteomics and Virus-Host Protein Interactions
Van Vliet, K.; Mohamed, M. R.; Zhang, L.; Villa, N. Y.; Werden, S. J.; Liu, J.; McFadden, G.
Microbiology and Molecular Biology Reviews, 2009, 73 (4), 730-749

Structural Basis for Parathyroid Hormone-Related Protein Binding to the Parathyroid Hormone Receptor and Design of Conformation-Selective Peptides
Pioszak, A. A.; Parker, N. R.; Gardella, T. J.; Xu, H. E.
Journal of Biological Chemistry, 2009, 284, 28382-28391

Structure of IL-33 and Its Interaction with the ST2 and IL-1RAcP Receptors - Insight into Heterotrimeric IL-1 Signaling Complexes
Lingel, A.; Weiss, T. M.; Niebuhr, M.; Pan, B.; Appleton, B. A.; Wiesmann, C.; Bazan, J. F.; Fairbrother, W. J.
Structure, 2009, 17 (10), 1398-1410

A Predictive High-Throughput Scale-Down Model of Monoclonal Antibody Production in CHO Cells
Legmann, R.; Schreyer, H. B.; Combs, R. G.; McCormick, E. L.; Russon, A. P.; Rodgers, S. T.
Biotechnology and Bioengineering, 2009, 104 (6), 1107-1120

Fluidics-Free Molecular Interactions Analysis.
Witte, K.
Genetic and Engineering News, 2009, July 1, 29 (13)

Who Needs Labels? Macromolecular Interaction Sans Labels.
Perkel, J. M.
Science, 2009, Sep. 19, 1561

Direct Optical Detection in Fragment-Based Screening.
Proll, F.; Fechner, P.; Proll, G.
Analytical and Bioanalytical Chemistry, 2009, 393, 1557 - 1562

A Global Benchmark Study Using Affinity-based Biosensors.
Rich, R.L. and others
Analytical Biochemistry, 2009, 386 (2), 194-216

Human Antibodies to Human Delta Like Ligand 4.
Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.
Regeneron Pharmaceuticals Inc., United States Patent 7,534,868

Antibodies to the PcrV Antigen of Pseudomonas Aeruginosa.
Bebbington, C. R.; Luehrsen, K.; Yarranton, G. T.; Baer, M.
KaloBios Pharmaceuticals Inc., United States Patent Application 20090191186

Universal Fibronectin Type III Binding-Domain Libraries.
Cappuccilli, G.; Crea, R.; Shen, R.; Hokanson, C. A.; Kirk, P. B.; Liston, D. R.
ProtElix, Inc., United States Patent Application 20090176654

Human Antibodies to Human Delta Like Ligand 4.
Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.
Regeneron Pharmaceuticals Inc., United States Patent Application 20090142354

Compositions that Bind Multiple Epitopes of IGF-1R.
Glaser, S.; Demarest, S.; Miller, B. R.; Hariharan, K.; Ho, S.; Dong, J.; Lugovskoy, A. A.
United States Patent Application 20090130105

Novel Rabbit Antibody Humanization Methods and Humanized Rabbit Antibodies.
Kovacevich, B. R.; Latham, J.
Alder Biopharmaceuticals Inc., United States Patent Application 20090104187

Label-free, Real-time Detection System for Molecular Interaction Analysis.
Lotze, M. T.
The University of Pittsburgh, United States Patent Application 20090147264

High Affinity Human Antibodies to Human Nerve Growth Factor.
MacDonald, L.; Torres, R.; Morra, M. R.; Martin, J. H.; Reinhardt, J. C.
Regeneron Pharmaceuticals Inc., United States Patent Application 20090041717

Antibodies to IL-6 and Use Thereof.
Garcia-Martinez, L.; Jensen, A. E. C.; Olson, K.; Dutzar, B.; Ojala, E.; Kovacevich, B.; Latham, J.; Smith, J. T. L.
Alder Biopharmaceuticals Inc., United States Patent Application 20090028784

Antibodies to TNF Alpha and Use Thereof.
Olson, K.; Dutzar, B.; Jensen, A. E. C.; Garcia-Martinez, L.; Ojala, E.; Latham, J.
Alder Biopharmaceuticals Inc., United States Patent Application 20090022659

Human Antibodies to Human Delta-like Ligand 4.
Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.
Regeneron Pharmaceuticals, Inc., United States Patent Application 20090017035

Exploring Blocking Assays Using Octet, ProteOn, and Biacore Biosensors.
Abdiche, Y. N.; Malashock, D. S.; Pinkerton, A; Pons, J.
Analytical Biochemistry, 2009, 386(2), 172-180

Human Antibodies to Human Delta-like Ligand 4.
Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.
Regeneron Pharmaceuticals, Inc., United States Patent 7,488,806

Novel Rabbit Antibody Humanization Methods and Humanized Rabbit Antibodies
Kovacevich, B. R.; Latham, J.
Alder Biopharmaceuticals Inc., United States Patent Application 20090238825

Novel Compositions and Methods for the Treatment of Immune Related Diseases
Clark, H.; Eaton, D.; Gonzalez, L.; Grogan, J.; Hackney, J. A.; Harden, K.; Yu, X.
Genentech, Inc., United States Patent Application 20090258013

Method of Treatment and Prophylaxis of Diseases Related to Amyloid Deposition Using IGM
Scuderi, J. R. P.; Safavi, A.; Langevin, M. G.
Talecris Biotherapeutics, Inc., United States Patent Application 20090269359

Antagonists of IL-6 to Prevent or Treat Cachexia, Weakness, Fatigue and/or Fever
Smith, J. T. L.; Schatzman, R. C.; Litton, M. J.; Latham, J.
Alder Biopharmaceuticals Inc., United States Patent Application 20090291077

Antagonists of IL-6 to Raise Albumin and/or Lower CRP
Smith, J. T. L.
Alder Biopharmaceuticals Inc., United States Patent Application 20090291082

Antagonists of IL-6 to Prevent or Treat Thrombosis
Smith, J. T. L.
Alder Biopharmaceuticals Inc., United States Patent Application 20090291089

Antibodies to IL-6 and Use Thereof
Garcia-Martinez, L. and others
Alder Biopharmaceuticals Inc., United States Patent Application 20090297436

Antibodies to IL-6 and Use Thereof
Garcia-Martinez, L. and others
Alder Biopharmaceuticals Inc., United States Patent Application 20090297513

2008

A Rapid Method for Determining Dynamic Binding Capacity of Resins for the Purification of Proteins.
Do, T.; Ho, F.; Heidecker, B.; Witte, K.; Chang, L.; Lerner, L.
Protein Expression and Purification, 2008, 60, 147-150

The Surface Protein TIGIT Suppresses T Cell Activation by Promoting the Generation of Mature Immunoregulatory Dendritic Cells.
Yu, X.; Harden, K.; Gonzalez, L. C.; Francesco, M.; Chiang, E.; Irving, B.; Tom, I.; Ivelja, S.; Refino, C. J.; Clark, H.; Eaton, D.; Grogan, J. L.
Nature Immunology, 2008, 10, 48-57

Advantages and Application of Label-free Detection Assays in Drug Screening.
Cunningham, B. T.; Laing, L. G.
Expert Opinion on Drug Discovery, 2008, 3(8), 891-901

Humaneered Anti-factor B Antibody.
Emlen, W.; Holers, V. M.; Flynn, P.
Taligen Therapeutics, Inc., United States Patent Application 20080299114

Antibodies to Lymphotoxin-Alpha.
Adams, C. W.; Grogan, J. L.; Gurney, A. L.; McCutcheon, K.
Genentech Inc., WIPO Patent Application No. WO2008063776.

Human Antibodies to Human Delta-like Ligand 4.
Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.
Regeneron Pharmaceuticals, Inc., United States Patent Application 20080181899

High Affinity Human Antibodies to Human IL-4 Receptor.
Stevens, S.; Huang, T. T.; Martin, J. H.; Farihurst, J. L.; Rafique, A.; Torres, M.; Pobursky, K. J.; Leidich, R. W.; Windsor, J. A.; Mikulka, W. R.; Ahrens, D. M.; Shi, E.; Papadopoulos, N. J.
Regeneron Pharmaceuticals, Inc., United States Patent Application 20080160035

Probing the Binding Mechanism and Affinity of Tanezumab, a Recombinant Humanized Anti-NGF Monoclonal Antibody, Using a Repertoire of Biosensors.
Abdiche, Y. N.; Malashock, D. S.; Pons, J.
Protein Science, 2008, 17(8), 1326-1335

Determining Kinetics and Affinities of Protein Interactions Using a Parallel Real-time Label-free Biosensor, the Octet.
Abdiche, Y.N.; Malashock, D. S.; Pinkerton, A; Pons, J.
Analytical Biochemistry, 2008, 377(2), 209-217

WNT Antagonists and Their Use in the Diagnosis and Treatment of WNT-mediated Disorders.
Ernest, J. A.; Polakis, P.; Rubinfeld, B.; Dealmeida, V. I.
Genentech, Inc., United States Patent Application 20080299136

2007

Detecting DNA: Getting and Begetting Cancer.
Farkas, A. M.; Kilgore, T. M.; Lotze, M. T.
Current Opinion in Investigational Drugs, 2007, 8, 981-986

Culture Method for Obtaining a Clonal Population of Antigen-specific B Cells.
Jensen, A. E. C.; Garcia, L.; Ojala, E.; Latham, J.
Alder Biopharmaceuticals, Inc., United States Patent Application 20070269868

Label-free Optical Biosensors in Drug Discovery.
Fang, Y.
Trends in Biopharmaceutical Industry, 2007, 3, 34-38

Higher-throughput, label-free, real-time molecular interaction analysis.
Rich, R. L.; Myszka, D. G.
Analytical Biochemistry, 2007, 361, 1-6

2006

Optical Biosensors: Where Next and How Soon?
Cooper, M. A.
Drug Discovery Today, 2006, 11 (23-24), 1061-1067

Current Biosensor Technologies in Drug Discovery.
Cooper, M. A.
Drug Discovery World, 2006, 68-82