Biosensor Types
Ready-to-Use
Octet biosensors are configured in a standard 96-well format. Biosensors simplify quantitation and kinetics by eliminating throughput limitations caused by microfluidic flow, surface regeneration, and sample purification.
Octet biosensor tips are coated with a proprietary biocompatible matrix that is uniform, non-denaturing, and has minimal non-specific binding. The tips are derivatized and ready for use in specific biomolecular applications. Various molecules can be attached to the surface, and multiple layers can be bound to study a myriad of biological interactions.
Each type of Octet Biosensor is designed to analyze specific biomolecular interactions. A range of surface chemistries is available, with choices of grade and binding capacity. Refer to the table below to select the appropriate grade for your needs:
Octet Biosensor Grades
Grade |
Description |
Quantitation Grade |
Ready to use for protein quantitation based on a standard calibration or yes/no binding |
Screening Grade |
Kinetic screening applications with off-rates < 15 minutes. Also ideal for custom quantitation assays. |
Kinetics Grade |
Kinetic characterization applications with baselines stable for 1 hour. Can be used for custom quantitation assays. |
|
Octet Biosensor Surface Chemistries
Surface Chemistry |
Available Grades |
Defining Characteristics |
Amine Reactive |
Screening
Kinetics |
Covalently couples any protein of interest with a primary amine to measure binding and kinetic characterization. |
Super Streptavidin |
Screening
Kinetics |
Streptavidin coated biosensor for small molecule analysis on the Octet RED System. Covalently bind small molecules or small peptides. |
Streptavidin
High Binding
|
Screening
Kinetics |
Streptavidin coated biosensor with a higher binding capacity than the standard binding capacity. Ideal for applications involving custom quantitation and the screening of FAbs, peptides and smaller proteins. |
Streptavidin SBC
(Standard Binding Capacity) |
Screening
Kinetics |
Streptavidin-coated biosensors for covalent binding of biotinylated proteins. |
Protein A |
Quantitation |
Protein A Biosensors provide concentration determination typically within the range of 1–500 µg/mL. |
Anti-murine IgG |
Quantitation |
Anti-mIgG F(ab')2 biosensors provide concentration determination for either mouse or rat IgG samples. |
Anti-human IgG
FC-Specific |
Quantitation |
Anti-human IgG, Fc Specific Biosensors provide concentration determination typically within the range of 1–100 µg/mL. |
Aminopropylsilane (APS) |
Kinetic |
Hydrophobic or electrostatic immobilization of most proteins. |
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Biosensor Selection
Quantitation

Kinetics
Suggest a Biosensor
Ideas for new biosensors are always welcome. Use our biosensor suggestion form to send your recommendation for a new biosensor offering to the ForteBio product development team.
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