 |  | |
| Improving the Accuracy, Speed, and Reproducibility of Titer Determination for the Clone Selection Process
Presented at: IBC 08 Antibody Production, San Diego, CA
By: Keith A. Davis, Ph.D., Scientist
WPGRD, Global Biologics, Pfizer Inc
Accurate titer determination remains a challenge, for Cell Line Development, with less than desirable precision, accuracy, and throughput. A new technology was evaluated that provides a > 10x decrease in hands-on time and turnaround time vs. both HPLC and ELISA while providing accuracy and precision comparable to that of Protein A HPLC without the HPLC waste or maintenance. |
 |
| | |
| Introducing the Octet as a reliable novel biosensor in characterizing protein/protein interactions Yasmina Abdiche, PhD
Rinat Laboratories, Pfizer Inc, South San Francisco, CA 94080
The presentation describes the study of protein/protein interactions using the Octet, a novel parallel-processing label-free biosensor. Two applications are described, namely “1-shot kinetics” and blocking, and examples are provided to demonstrate that the technology is reliable when compared with Biacore. The Octet is a simple dip-and-read assay that harnesses bio-layer interferometry to detect molecular level interactions in real time through the use of disposable fiber-optic biosensors. The Octet is emerging as an attractive low-cost complement to Biacore.
|
|
| | |
| Technology Workshop presented at BioProcess International in Boston, MA Title: Use of ForteBIO Octet for Quantitative Titer Analysis in Biopharmaceutical Development |
|
| | |
| Presentation given by León García-Martínez, Ph.D., Associate Director of Antibody Therapeutics, Alder Biopharmaceuticals Presented at Screening Europe, Barcelona, Spain in February 07
|
|
| | |
| Presentation given by Pete Flynn, Director of Biochemistry Research, Kalobios Pharmaceuticals Presented at 17th Annual Antibody Engineering Conference in San Diego, CA in December ‘06
|
|
| | |
| Presented by Dr. Laura Lerner at Bioprocess International '06, San Francisco, CA |
|
| | |
| Poster presentation by Raven Biotechnologies @ WilBio Waterside conference in Chicago, IL - 2006 |
|
