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The Structure of SHH in Complex with HHIP Reveals a Recognition Role for the Shh Pseudo Active Site in SignalingBosanac, I.; Maun, H.R.; Scales, S.J.; Wen, X.; Lingel, A.; Bazan, J.F.; de Sauvage, F.J.; Hymowitz, S.G.; Lazarus, R.A.Nature Structural & Molecular Biology, 2009, 16 (7), 691 - 698.
Label-free Detection of Biomolecular Interactions Using BioLayer Interferometry for Kinetic Characterization.Concepcion, J and othersCombinatorial Chemistry and High Throughput Screening, 2009, 12, 791 - 800
Fluidics-Free Molecular Interactions Analysis.Witte, K.Genetic and Engineering News, 2009, July 1, 29 (13)
Who Needs Labels? Macromolecular Interaction Sans Labels.Perkel, J. M.Science, 2009, Sep. 19, 1561
Direct Optical Detection in Fragment-Based Screening.Proll, F.; Fechner, P.; Proll, G.Analytical and Bioanalytical Chemistry, 2009, 393, 1557 - 1562
Human Antibodies to Human Delta Like Ligand 4.Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.Regeneron Pharmaceuticals Inc., United States Patent 7,534,868
Antibodies to the PcrV Antigen of Pseudomonas Aeruginosa.Bebbington, C. R.; Luehrsen, K.; Yarranton, G. T.; Baer, M.KaloBios Pharmaceuticals Inc., United States Patent Application 20090191186
Universal Fibronectin Type III Binding-Domain Libraries.Cappuccilli, G.; Crea, R.; Shen, R.; Hokanson, C. A.; Kirk, P. B.; Liston, D. R.ProtElix, Inc., United States Patent Application 20090176654
Human Antibodies to Human Delta Like Ligand 4.Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.Regeneron Pharmaceuticals Inc., United States Patent Application 20090142354
Compositions that Bind Multiple Epitopes of IGF-1R.Glaser, S.; Demarest, S.; Miller, B. R.; Hariharan, K.; Ho, S.; Dong, J.; Lugovskoy, A. A.United States Patent Application 20090130105
Novel Rabbit Antibody Humanization Methods and Humanized Rabbit Antibodies.Kovacevich, B. R.; Latham, J.Alder Biopharmaceuticals Inc., United States Patent Application 20090104187
Label-free, Real-time Detection System for Molecular Interaction Analysis.Lotze, M. T.The University of Pittsburgh, United States Patent Application 20090147264
A Global Benchmark Study Using Affinity-based Biosensors.Rich, R.L. and othersAnalytical Biochemistry, 2009, 386 (2), 194-216
High Affinity Human Antibodies to Human Nerve Growth Factor.MacDonald, L.; Torres, R.; Morra, M. R.; Martin, J. H.; Reinhardt, J. C.Regeneron Pharmaceuticals Inc., United States Patent Application 20090041717
Antibodies to IL-6 and Use Thereof.Garcia-Martinez, L.; Jensen, A. E. C.; Olson, K.; Dutzar, B.; Ojala, E.; Kovacevich, B.; Latham, J.; Smith, J. T. L.Alder Biopharmaceuticals Inc., United States Patent Application 20090028784
Antibodies to TNF Alpha and Use Thereof.Olson, K.; Dutzar, B.; Jensen, A. E. C.; Garcia-Martinez, L.; Ojala, E.; Latham, J.Alder Biopharmaceuticals Inc., United States Patent Application 20090022659
Human Antibodies to Human Delta-like Ligand 4.Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.Regeneron Pharmaceuticals, Inc., United States Patent Application 20090017035
Exploring Blocking Assays Using Octet, ProteOn, and Biacore Biosensors.Abdiche, Y. N.; Malashock, D. S.; Pinkerton, A; Pons, J.Analytical Biochemistry, 2009, 386(2), 172-180
Human Antibodies to Human Delta-like Ligand 4.Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.Regeneron Pharmaceuticals, Inc., United States Patent 7,488,806
A Rapid Method for Determining Dynamic Binding Capacity of Resins for the Purification of Proteins.Do, T.; Ho, F.; Heidecker, B.; Witte, K.; Chang, L.; Lerner, L.Protein Expression and Purification, 2008, 60, 147-150
The Surface Protein TIGIT Suppresses T Cell Activation by Promoting the Generation of Mature Immunoregulatory Dendritic Cells.Yu, X.; Harden, K.; Gonzalez, L. C.; Francesco, M.; Chiang, E.; Irving, B.; Tom, I.; Ivelja, S.; Refino, C. J.; Clark, H.; Eaton, D.; Grogan, J. L.Nature Immunology, 2008, 10, 48-57
Advantages and Application of Label-free Detection Assays in Drug Screening.Cunningham, B. T.; Laing, L. G.Expert Opinion on Drug Discovery, 2008, 3(8), 891-901
Humaneered Anti-factor B Antibody.Emlen, W.; Holers, V. M.; Flynn, P.Taligen Therapeutics, Inc., United States Patent Application 20080299114
Antibodies to Lymphotoxin-Alpha.Adams, C. W.; Grogan, J. L.; Gurney, A. L.; McCutcheon, K.Genentech Inc., WIPO Patent Application No. WO2008063776.
Human Antibodies to Human Delta-like Ligand 4.Papadopoulos, N. J.; Martin, J. H.; Smith, E.; Noguera-Troise, I.; Thurston, G.Regeneron Pharmaceuticals, Inc., United States Patent Application 20080181899
High Affinity Human Antibodies to Human IL-4 Receptor.Stevens, S.; Huang, T. T.; Martin, J. H.; Farihurst, J. L.; Rafique, A.; Torres, M.; Pobursky, K. J.; Leidich, R. W.; Windsor, J. A.; Mikulka, W. R.; Ahrens, D. M.; Shi, E.; Papadopoulos, N. J.Regeneron Pharmaceuticals, Inc., United States Patent Application 20080160035
Probing the Binding Mechanism and Affinity of Tanezumab, a Recombinant Humanized Anti-NGF Monoclonal Antibody, Using a Repertoire of Biosensors.Abdiche, Y. N.; Malashock, D. S.; Pons, J.Protein Science, 2008, 17(8), 1326-1335
Determining Kinetics and Affinities of Protein Interactions Using a Parallel Real-time Label-free Biosensor, the Octet.Abdiche, Y.N.; Malashock, D. S.; Pinkerton, A; Pons, J.Analytical Biochemistry, 2008, 377(2), 209-217
WNT Antagonists and Their Use in the Diagnosis and Treatment of WNT-mediated Disorders.Ernest, J. A.; Polakis, P.; Rubinfeld, B.; Dealmeida, V. I.Genentech, Inc., United States Patent Application 20080299136
Detecting DNA: Getting and Begetting Cancer.Farkas, A. M.; Kilgore, T. M.; Lotze, M. T.Current Opinion in Investigational Drugs, 2007, 8, 981-986
Culture Method for Obtaining a Clonal Population of Antigen-specific B Cells.Jensen, A. E. C.; Garcia, L.; Ojala, E.; Latham, J.Alder Biopharmaceuticals, Inc., United States Patent Application 20070269868
Label-free Optical Biosensors in Drug Discovery.Fang, Y.Trends in Biopharmaceutical Industry, 2007, 3, 34-38
Higher-throughput, label-free, real-time molecular interaction analysis.Rich, R. L.; Myszka, D. G.Analytical Biochemistry, 2007, 361, 1-6
Optical Biosensors: Where Next and How Soon?Cooper, M. A.Drug Discovery Today, 2006, 11 (23-24), 1061-1067
Current Biosensor Technologies in Drug Discovery.Cooper, M. A.Drug Discovery World, 2006, 68-82
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