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2017

  Vesicular Stomatitis Virus N Protein-specific Single-domain Antibody Fragments Inhibit Replication
Hanke L, et al., EMBO Rep, 18(6):1027-1037, 2017

  Tumor-secreted Anterior Gradient-2 Binds to VEGF and FGF2 and Enhances Their Activities by Promoting Their Homodimerization
Guo H, et al., Oncogene, doi: 10.1038/onc.2017.132, 2017

  Enhancement of Antibody Functions Through Fc Multiplications
Wang Q, et al., Mabs, 9(3):393-403, 2017

  Immunodominant Protein MIP_05962 from Mycobacterium Indicus Pranii Displays Chaperone Activity
Sharma A, et al., FEBS J, 284(9):1338-1354, 2017

  Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1
Saito T, et al., Cell Rep, 19(9):1917-1928, 2017

  Binding of the Methyl Donor S-Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2'-O-Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10
Aouadi W, et al., J Virol, 91(5). pii: e02217-16, 2017

  Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop
Cale EM, et al., Immunity, 46(5):777-791.e10, 2017

  Autophosphorylation-based Calcium (Ca2+) Sensitivity Priming and Ca2+/Calmodulin Inhibition of Arabidopsis thaliana Ca2+-dependent Protein Kinase 28 (CPK28)
Bender KW, et al., J Biol Chem, 292(10):3988-4002, 2017

2016

  Fragment-Linking Approach Using 19F NMR Spectroscopy To Obtain Highly Potent and Selective Inhibitors of β‑Secretase
Jordan JB et al., J Med Chem, 59: 3732-3749, 2016

  Immunodominant West Nile Virus T Cell Epitopes Are Fewer in Number and Fashionably Late
Kaabinejadian S, et al., J Immunol, 196: 4263-4273, 2016

  Protein-Flavonoid Interaction Studies by a Taylor Dispersion Surface Plasmon Resonance (SPR) Technique: A Novel Method to Assess Biomolecular Interactions
Vachali PP, Li B, Besch B, Bernstein PS, Biosensors, 6(6), 2016

2015

  Measurement of Free Versus Total Therapeutic Monoclonal Antibody in Pharmacokinetic Assessment is Modulated by Affinity, Incubation Time, and Bioanalytical Platform
Talbot JJ, et al., AAPS J, 17(6):1446-54, 2015

  Dengue Virus prM-Specific Human Monoclonal Antibodies with Virus Replication-Enhancing Properties Recognize a Single Immunodominant Antigenic Site
Smith S, et al., J Virol, 90(2):780-9, 2015

  A Search for Synergy in the Binding Kinetics of Trastuzumab and Pertuzumab Whole and F(ab) to Her2
Lua WH, et al., npj Breast Cancer, doi:10.1038/npjbcancer.2015.12, 2015

  Restoring Anticancer Immune Response by Targeting Tumor-Derived Exosomes With a HSP70 Peptide Aptamer
Gobbo J, et al., J Natl Cancer Inst, 108(3). pii: djv330, 2015

  Conserved Role of an N-Linked Glycan on the Surface Antigen of Human Immunodeficiency Virus Type 1 Modulating Virus Sensitivity to Broadly Neutralizing Antibodies against the Receptor and Coreceptor Binding Sites
Townsley S, et al., J Virol., 28;90(2):829-41, 2015

  Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody
Cheng C, et al., J Virol., 90(6):2740-55, 2015

  H5N1 Vaccine-Elicited Memory B Cells Are Genetically Constrained by the IGHV Locus in the Recognition of a Neutralizing Epitope in the Hemagglutinin Stem
Wheatley A, et al., J Immunol, 195(2):602-10, 2015

  Heat Shock Protein 90 Mediates the Apoptosis and Autophage in Nicotinic-Mycoepoxydiene-Treated HeLa Cells
Sun Y, et al., Acta Biochim Biophys Sin (Shanghai), 47(6):451-8, 2015

  Helicobacter Pylori FlhA Binds the Sensor Kinase and Flagellar Gene Regulatory Protein FlgS with High Affinity
Tsang J, et al., J Bacteriol, 197(11):1886-92, 2015

  Heterogeneous IgG Interacts with FcRn and Its Transport Across Gastrointestinal Barrier
Pang G, et al., Food and Agricultural Immunology, DOI:10.1080/09540105.2014.918588, 2015

  High Throughput Cross-Interaction Measures for Human IgG1 Antibodies Correlate with Clearance Rates in Mice
Kelly R, et al., MAbs, 7(4):770-7, 2015

  Identification and Structure Solution of Fragment Hits Against Kinetoplastid N-Myristoyltransferase
Robinson D, Wyatt P, Acta Crystallogr F Struct Biol Commun , 71(Pt 5):586-93, 2015

  Identification of a Common Epitope Between Enterovirus 71 and Human MED25 Proteins Which May Explain Virus-Associated Neurological Disease
Fan P, et al., Viruses, 27;7(4):1558-77, 2015

  Identification of Malaria Parasite-Infected Red Blood Cell Surface Aptamers by Inertial Microfluidic SELEX (I-SELEX)
Birch C, et al., Sci Rep, 1;5:11347, 2015

  Identification of the Base-Pairing Requirements for Repression of hctA Translation by the Small RNA IhtA Leads to the Discovery of a New mRNA Target in Chlamydia trachomatis
Grieshaber N, et al., PLoS One , 10(3):e0116593, 2015

  Immunotherapy Based on Bispecific T-Cell Engager with hIgG1 Fc Sequence as a New Therapeutic Strategy in Multiple Myeloma
Zou J, et al., Cancer Sci, 106(5):512-21, 2015

  In Silico Discovery and Validation of Potent Small-Molecule Inhibitors Targeting the Activation Function 2 Site of Human Oestrogen Receptor α
Singh K, et al., Breast Cancer Res, 17:27, 2015

  Inhibition of Type VI Secretion by an Anti-TssM Llama Nanobody
Nguyen V, et al., PLoS One , 10(3):e0122187, 2015

  Interaction of AIM with Insulin-Like Growth Factor-Binding Protein-4
You Q, et al., Int J Mol Med, Epub ahead of print, 2015

  Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity Against Chikungunya Virus
Smith S, et al., Cell Host Microbe, 18(1):86-95, 2015

  Kinetics Characterization of Ligand-Receptor Interactions Using Oblique-Incidence Reflectivity Difference Method
Liu S, Yang G, Methods in Pharmacology and Toxicology, pp 111-118, 2015

  Mapping and Quantitation of the Interaction Between the Recombination Activating Gene Proteins RAG1 and RAG2
Zhang Y, et al., J Biol Chem, 290(19):11802-17, 2015

  Maturation of the Proteasome Core Particle Induces an Affinity Switch That Controls Regulatory Particle Association
Wani P, et al., Nat Commun , doi: 10.1038/ncomms7384, 2015

  Measuring Protein-Protein and Protein-Nucleic Acid Interactions by Bio-Layer Interferometry
Sultana A, Lee J, Curr Protoc Protein Sci, 79:19.25.1-19.25.26, 2015

  Mechanism of Human Antibody-Mediated Neutralization of Marburg Virus
Flyak A, et al., Cell, 160(5):893-903, 2015

  Mechanisms Mediating Enhanced Neutralization Efficacy of Staphylococcal Enterotoxin B by Combinations of Monoclonal Antibodies
Dutta K, et al., J Biol Chem , 13;290(11):6715-30, 2015

  Milk Matrix Effects on Antibody Binding Analyzed by Enzyme-Linked Immunosorbent Assay and Bio-Layer Interferometry
Brandon D, Adams L, J Agric Food Chem , 63(13):3593-8, 2015

  Molecular Determinants of Polyubiquitin Recognition by Continuous Ubiquitin-Binding Domains of Rad18
Thach T, et al., Biochemistry, 54(12):2136-48, 2015

  Moraxella catarrhalis Binds Plasminogen to Evade Host Innate Immunity
Singh B, et al., Infect Immun, Epub ahead of print, 2015

  mRNA Maturation in Giant Viruses: Variation on a Theme
Priet S, et al., Nucleic Acids Res, 20;43(7):3776-88, 2015

  Mycobacterium tuberculosis RpfE Promotes Simultaneous Th1- and Th17-Type T-cell Immunity via TLR4-Dependent Maturation of Dendritic Cells
Choi H, et al., Eur J Immunol, 45(7):1957-71, 2015

  Nonbinding Site-Directed Mutants of Transferrin Binding Protein B Exhibit Enhanced Immunogenicity and Protective Capabilities
Frandoloso R, et al., Infect Immun, 83(3):1030-8, 2015

  Novel Mechanism of Regulation of Tomato Bushy Stunt Virus Replication by Cellular WW-Domain Proteins
Barajas D, et al., J Virol, 89(4):2064-79, 2015

  Oligomerization of FtsZ Converts the FtsZ Tail Motif (CCTP) into a Multivalent Ligand with High Avidity for Partners ZipA and SlmA
Du S, Park K, Lutkenhaus J, Mol Microbiol, 95(2):173-88, 2015

  Oncogenic and RASopathy-Associated K-RAS Mutations Relieve Membrane-Dependent Occlusion of the Effector-Binding Site
Mazhab-Jafari M, et al., Proc Natl Acad Sci U S A, 112(21):6625-30, 2015

  Patient-Specific Neutralizing Antibody Responses to Herpes Simplex Virus are Attributed to Epitopes on Either gD, gB, or Both and Can Be Type-Specific
Cairns T, et al., J Virol, pii: JVI.01213-15, 2015

  Plasmodium falciparum Adhesion Domains Linked to Severe Malaria Differ in Blockade of Endothelial Protein C Receptor
Sampath S, et al., Cell Microbiol, DOI: 10.1111/cmi.12478, 2015

  Predicting the Uncertain Future of Aptamer-Based Diagnostics and Therapeutics
Bruno J, Molecules, 20(4):6866-87, 2015

  Preexisting Immunity, More Than Aging, Influences Influenza Vaccine Responses
Reber A, et al., Oxford Journals, doi: 10.1093/ofid/ofv052, 2015

  Antigenicity and Immunogenicity of a Trimeric Envelope Protein from an Indian Clade C HIV-1 Isolate
Sneha Priya R, et al., J Biol Chem, 290(14):9195-208, 2015

  Assembly of Cellulases with Synthetic Protein Scaffolds In Vitro
Yu T, et al., Bioresources and Bioprocessing, 2:16, 2015

  Bacterial Cytoplasmic Display Platform Retained Display (ReD) Identifies Stable Human Germline Antibody Frameworks
Beasley M, et al., Biotechnol J, 10(5):783-9, 2015

  Bio-Layer Interferometry of a Multivalent Sulfated Virus Nanoparticle with Heparin-Like Anticoagulant Activity
Groner M, etal., Anal Bioanal Chem, 407(19):5843-7, 2015

  Biophysical Measurement of the Balance of Influenza A Hemagglutinin and Neuraminidase Activities
Benton D, et al., J Biol Chem, 290(10):6516-21, 2015

  Biophysical Methods for Identifying Fragment-Based Inhibitors of Protein-Protein Interactions
Pfaff S, et al., Methods Mol Biol, 1278:587-613, 2015

  BMI1-RING1B is an Autoinhibited RING E3 Ubiquitin Ligase
Taherbhoy A, Huang O, Cochran A, Nat Commun, 5.542361111, 2015

  Boosting Antibody Developability Through Rational Sequence Optimization
Seeliger D, et al., MAbs, 7(3):505-15, 2015

  Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Non-Human Primates from Mucosal Simian-Human Immunodeficiency Virus Infection
Saunders K, et al., J Virol, doi: 10.1128/JVI.00908-15, 2015

  Cellular Uptake and Ultrastructural Localization Underlie the Pro-Apoptotic Activity of a Hydrocarbon-Stapled BIM BH3 Peptide
Edwards A, et al., ACS Chem Biol, DOI: 10.1021/acschembio.5b00214, 2015

  Characterization of Protective Immune Response Elicited by a Trimeric Envelope Protein from an Indian Clade C HIV-1 Isolate in Rhesus Macaques
Menon V, et al., J Med Primatol, doi: 10.1111/jmp.12178, 2015

  Circulating Levels of sFlt1 Splice Variants as Predictive Markers for the Development of Preeclampsia
Souders C, et al., Int J Mol Sci, 16(6):12436-53, 2015

  Comparable Antigenicity and Immunogenicity of Oligomeric Forms of a Novel, Acute HIV-1 Subtype C gp145 Envelope for Use in Preclinical and Clinical Vaccine Research
Wieczorek L, et al., J Virol, 89(15):7478-93, 2015

  Conditional Trimerization and Lytic Activity of HIV-1 gp41 Variants Containing the Membrane-Associated Segments
Dai Z, et al., Biochemistry, 54(8):1589-99, 2015

  Construction of an Antimyoglobin Single-Chain Variable Fragment with Rapid Reaction Kinetics
Jang J, et al., Biotechnol Appl Biochem, DOI: 10.1002/bab.1349, 2015

  Crystal Structure of the Bloom's Syndrome Helicase Indicates a Role for the HRDC Domain in Conformational Changes
Newman J, et al., Nucleic Acids Res, 43(10):5221-35, 2015

  Crystal Structure, Conformational Fixation and Entry-Related Interactions of Mature Ligand-Free HIV-1 Env
Do Kwon Y, et al., Nat Struct Mol Biol, 22(7):522-31, 2015

  C-Terminal Amino Acids Are Essential for Human Heat Shock Protein 70 Dimerization
Marcion G, et al., Cell Stress and Chaperones, pp 61-72, 2015

  Detection of Mycobacterium tuberculosis Based on H37Rv Binding Peptides Using Surface Functionalized Magnetic Microspheres Coupled with Quantum Dots - A Nano Detection Method for Mycobacterium Tuberculosis
Yang H, et al., Int J Nanomedicinev, 10:77-88, 2015

  Directed Evolution of a Yeast-Displayed HIV-1 SOSIP gp140 Spike Protein Toward Improved Expression and Affinity for Conformational Antibodies.
Grimm S, Battles M, Ackerman M, PLoS One, 10(2), 2015

  Directed Evolution of anti-HER2 DARPins by SNAP display reveals stability/function trade-offs in the selection process
Houlihan G, et al., Protein Eng Des Sel, pii: gzv029 Epub ahead of print, 2015

  Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP
van Adrichem A, et al., Comb Chem High Throughput Screen, 18(1):3-17, 2015

  Dose-Dependent Biphasic Leptin-Induced Proliferation Is Caused by Non-Specific IL-6/NF-κB Pathway Activation in Human Myometrial Cells
Barrichon M, et al., Br J Pharmacol, 172(12):2974-90, 2015

  During Cytochrome c Maturation CcmI Chaperones Class I Apocytochromes Until the Formation of Their b-Type Cytochrome Intermediates
Verissimo A, Shroff N, Daldal F, J Biol Chem, 290(27):16989-7003., 2015

  Exploiting Light Chains for the Scalable Generation and Platform Purification of Native Human Bispecific IgG
Fischer N, et al., Nat Commun, doi: 10.1038/ncomms7113, 2015

  Exploration of the HIF-1α/p300 Interface Using Peptide and Adhiron Phage Display Technologies
Kyle H, et al., Mol Biosyst, DOI: 10.1039/C5MB00284B, 2015

  Five Birds, One Stone: Neutralization of α-Hemolysin and 4 bi-Component Leukocidins of Staphylococcus aureus with a Single Human Monoclonal Antibody
Rouha H, et al., MAbs, 7(1):243-54, 2015

  Generation and Characterization of Human Monoclonal Antibodies Targeting Anthrax Protective Antigen following Vaccination with a Recombinant Protective Antigen Vaccine
Chi X, et al., Clin Vaccine Immunol, 22(5):553-60, 2015

  Glutathione Activates Virulence Gene Expression of an Intracellular Pathogen
Reniere M, et al., Nature, 517(7533):170-3, 2015

  Group Selection and Contribution of Minority Variants During Virus Adaptation Determines Virus Fitness and Phenotype
Borderia A, et al., PLoS Pathog, 11(5):e1004838, 2015

  A Broadly Neutralizing Human Monoclonal Antibody Exhibits In Vivo Efficacy Against Both Human Metapneumovirus and Respiratory Syncytial Virus
Schuster J, et al., J Infect Dis, 211(2):216-25, 2015

  A Fully Human Monoclonal Antibody with Novel Binding Epitope and Excellent Neutralizing Activity to Multiple Human IFN-α Subtypes: a Candidate Therapy for Systemic Lupus Erythematosus
Du P, et al., MAbs, 7(5):969-80, 2015

  A High-Affinity Native Human Antibody Neutralizes Human Cytomegalovirus Infection of Diverse Cell Types
Kauvar L, et al., Antimicrob Agents Chemother, 59(3):1558-68, 2015

  A Human Monoclonal IgG That Binds Aβ Assemblies and Diverse Amyloids Exhibits Anti-Amyloid Activities In Vitro and In Vivo
Levites Y, et al., J Neurosci, 22;35(16):6265-76, 2015

  A Human-Infecting H10N8 Influenza Virus Retains a Strong Preference for Avian-Type Receptors
Zhang H, et al., Cell Host Microbe, 11;17(3):377-84, 2015

  A Multi-Pronged Investigation into the Effect of Glucose Starvation and Culture Duration on Fed-Batch CHO Cell Culture
Fan Y, et al., Biotechnol Bioeng, 112(10):2172-84, 2015

  A Mutant Tat Protein Inhibits HIV-1 Reverse Transcription by Targeting the Reverse Transcription Complex
Lin M, et al., J Virol, 89(9):4827-36, 2015

  A Novel In Vitro Assay to Predict Neonatal Fc Receptor-Mediated Human IgG Half-Life
Souders C, et al., MAbs, 7(5):912-21, 2015

  Acetylproteomic Analysis Reveals Functional Implications of Lysine Acetylation in Human Spermatozoa (sperm)
Yu H, et al., Mol Cell Proteomics, 14(4):1009-23, 2015

  Aerobic Growth of Escherichia coli Is Reduced and ATP Synthesis Is Selectively Inhibited When Five C-Terminal Residues Are Deleted from the ε Subunit of ATP Synthase
Shah N, Duncan T, J Biol Chem , 290(34):21032-41, 2015

  Amplification Systems of Weak Interaction Biosensors: Applications and Prospects
Wang X, et al., Emerald Insight, DOI: http://dx.doi.org/10.1108/SR-03-2014-629, 2015

  Antibody Mimetic Receptor Proteins for Label-Free Biosensors
Raina M, et al., Analyst, 140(3):803-10, 2015

  Immunogenicity Assessment of Biotherapeutic Products: An Overview of Assays and Their Utility
Wadhwa M, et al., Biologicals, 43(5):298-306, 2015

  Reverse Engineering of Vaccine Antigens Using High Throughput Sequencing-Enhanced mRNA Display
Nini Gu, et al., Science Direct, 2(8):857-65, 2015

  Therapeutic Intradermal Delivery of Tumor Necrosis Factor-Alpha Antibodies Using Tip-Loaded Dissolvable Microneedle Arrays
Korkmaz E, et al., Acta Biomater, pii: S1742-7061(15)00284-6, 2015

  pH Recycling Aqueous Two-Phase Systems Applied in Extraction of Maitake β-Glucan and Mechanism Analysis Using Low-Field Nuclear Magnetic Resonance
Hou 1, Cao X, J Chromatogr A, 1405:40-8, 2015

  Clinical Immunosensing of Tuberculosis CFP-10 Antigen in Urine Using Interferometric Optical Fiber Array
Kim J, et al., Science Direct, 10.1016/j.snb.2015.04.046, 2015

  Identification of Outer Membrane Porin D as a Vitronectin-binding Factor in Cystic Fibrosis Clinical Isolates of Pseudomonas Aeruginosa
Paulsson M, et al., J Cyst Fibros, pii: S1569-1993(15)00120-4, 2015

  Rapid and Sensitive Detection of Norovirus Antibodies in Human Serum with a Biolayer Interferometry Biosensor
Auer S, et al., Science Direct, doi:10.1016/j.snb.2015.06.088, 2015

  Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex
Kolumam G, et al., EBioMedicine, 2(7):730-43, 2015

  Optimal Fusion of Antibody Binding Domains Resulted in Higher Affinity and Wider Specificity
Dong J, et al., J Biosci Bioeng, pii: S1389-1723(15)00141-3, 2015

  Highly Stable Aptamers Selected from a 2'-Fully Modified fGmH RNA Library for Targeting Biomaterials
Friedman A, Kim D, Liu R, Biomaterials, 36:110-23, 2015

  A Newly Designed Molecule J2326 for Alzheimer's Disease Disaggregates Amyloid Fibrils and Induces Neurite Outgrowth
Chang P, et al., Neuropharmacology, 92:146-57, 2015

  Aptamers as a Replacement for Antibodies in Enzyme-Linked Immunosorbent Assay
Toh S, et al., Biosens Bioelectron, 64:392-403, 2015

2014

  The Identification, Analysis and Structure-Based Development of Novel Inhibitors of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase
Yun MK, et al., Bioorg & Med Chem, 22: 2157-2165, 2014

  Predicting the Origins of Anti-blood Group Antibody Specificity: A Case Study of the ABO A-and B-antigens Supplementary Material
Makeneni S, et al., Front Immunol, 22;5:397, 2014

  Recognition of the Small Regulatory RNA RydC by the Bacterial Hfq Protein
Dimastrogiovanni D, et al., Elife, 3 doi: 10.7554/eLife.05375, 2014

  Identification of a Misfolded Region in Superoxide Dismutase 1 that is Exposed in Amyotrophic Lateral Sclerosis
Rotunno MS, J Biol Chem, 289(41):28527-38, 2014

  Kinetic Titration Series with Biolayer Interferometry
Frenzel D, Willbold D., PLoS One, 9(9):e106882, 2014

  A Phospha-oseltamivir-biotin Conjugate as a Strong and Selective Adhesive for the Influenza Virus
Streicher H, et al., Bioorg Med Chem Lett, 24(7):1805-7, 2014

  Structure and Protein-protein Interactions of Methanol Dehydrogenase from Methylococcus Capsulatus (Bath)
Culpepper M, Rosenzweig A, Biochemistry, 53(39):6211-9, 2014

  The Spleen Tyrosine Kinase (Syk) Regulates Alzheimer Amyloid-β Production and Tau Hyperphosphorylation
Paris D, et al., J Biol Chem, 289(49):33927-44, 2014

  Strand-specific Recognition of DNA Damages by XPD Provides Insights into Nucleotide Excision Repair Substrate Versatility
Buechner C, et al., J Biol Chem , 289(6):3613-24, 2014

  Seed Sequence-matched Controls Reveal Limitations of Small Interfering RNA Knockdown in Functional and Structural Studies of Hepatitis C Virus NS5A-MOBKL1B Interaction
Chung H, et al., J Virol, 88(19):11022-33, 2014

  Chemical Biology. A bump-and-hole Approach to Engineer Controlled Selectivity of BET Bromodomain Chemical Probes
Baud M, et al., Science, 346(6209):638-41, 2014

  Structural and Biochemical Insights into the Activation Mechanisms of Germinal Center Kinase OSR1
Li C, et al., J Biol Chem , 289(52):35969-78, 2014

  Probing the Sites of Interactions of Rotaviral Proteins Involved in Replication
Viskovska M, et al., J Virol, 88(21):12866-81, 2014

  Development of a Protein Nanoparticle Platform for Targeting EGFR Expressing Cancer Cells
Jakob W, et al., Chemical Technology and Biotechnology, 90(7):1230-36, 2014

  Glypican-3-targeting F(ab')2 for 89Zr PET of Hepatocellular Carcinoma
Sham J, et al., J Nucl Med , 55(12):2032-7, 2014

  Plasmodium Falciparum Aldolase and the C-terminal Cytoplasmic Domain of Certain Apical Organellar Proteins Promote Actin Polymerization
Diaz S, et al., Mol Biochem Parasitol, 197(1-2):9-14, 2014

  Hyperglycosylated Stable Core Immunogens Designed to Present the CD4 Binding Site are Preferentially Recognized by Broadly Neutralizing Antibodies
Ingale J, et al., J Virol, 88(24):14002-16, 2014

  A von Willebrand Factor Fragment Containing the D'D3 Domains is Sufficient to Stabilize Coagulation Factor VIII in Mice
Yee A, et al., Blood, 124(3):445-52, 2014

  Exposure of Epitope Residues on the Outer Face of the Chikungunya Virus Envelope Trimer Determines Antibody Neutralizing Efficacy
Fong R, et al., J Virol, 88(24):14364-79, 2014

  MM-141, an IGF-IR- and ErbB3-directed Bispecific Antibody, Overcomes Network Adaptations that Limit Activity of IGF-IR Inhibitors
Fitzgerald J, et al., Mol Cancer Ther, 13(2):410-25, 2014

  Envelope Variants Circulating as Initial Neutralization Breadth Developed in Two HIV-infected Subjects Stimulate Multiclade Neutralizing Antibodies in Rabbits
Malherbe D, et al., J Virol, 88(22):12949-67, 2014

  Assembly and Architecture of the EBV B Cell Entry Triggering Complex
Sathiyamoorthy K, et al., PLoS Pathog, 10(8):e1004309, 2014

  Structural and Functional Insight into TAF1-TAF7, a Subcomplex of Transcription Factor II D
Bhattacharya S, et al., Proc Natl Acad Sci U S A, 111(25):9103-8, 2014

  Susceptibility to HLA-DM Protein is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide
Yin L, et al., J Biol Chem, 289(34):23449-64, 2014

  HSP70 Sequestration by Free α-globin Promotes Ineffective Erythropoiesis in β-thalassaemia
Arlet J, et al., Nature, 514(7521):242-6, 2014

  Manipulation of Receptor Oligomerization as a Strategy to Inhibit Signaling by TNF Superfamily Members
Warren J, et al., Sci Signal, 7(339):ra80, 2014

  Production and Characterization of Recombinant Human Beta-defensin DEFB120
Liu H, et al., J Pept Sci, doi: 10.1002/psc.2611, 2014

  Rapid Homogenous Time-Resolved Fluorescence (HTRF) Immunoassay for Anthrax Detection
Cohen N, et al., J Fluoresc, doi: 10.1007/s10895-014-1354-7, 2014

  Global Identification of O-GlcNAc Transferase (OGT) Interactors by a Human Proteome Microarray and the Construction of an OGT Interactome
Deng RP, et al., Proteomics, doi: 10.1002/pmic.201300144, 2014

  Talin-bound NPLY Motif Recruits Integrin-signaling Adapters to Regulate Cell Spreading and Mechanosensing
Pinon P, et al., J Cell Biol, 205(2):265-81, 2014

  Ca2+-Calmodulin Regulates SNARE Assembly and Spontaneous Neurotransmitter Release via v-ATPase Subunit V0a1
Wang D, et al., J Cell Biol, 205(1):21-31, 2014

  Structure of Vaccinia Virus A46, an Inhibitor of TLR4 Signaling Pathway, Shows the Conformation of VIPER Motif
Kim Y, et al., Protein Sci, doi: 10.1002/pro.2472, 2014

  ZMYND11 Links Histone H3.3K36me3 to Transcription Elongation and Tumour Suppression
Wen H, et al., Nature, 508(7495):263-8, 2014

  Sulfolobus replication factor C stimulates the activity of DNA polymerase B1
Xing X, et al., J Bacteriol, doi: 10.1128/JB.01552-14, 2014

  Structural determinants for binding of Sorting Nexin 17 (SNX17) to the cytoplasmic adaptor protein Krev Interaction Trapped 1 (KRIT1)*
Stiegler AL, et al., J Biol Chem, pii: jbc.M114.584011, 2014

  Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D
Bhattacharya S, et al., Proc Natl Acad Sci U S A, 111(25):9103-8, 2014

  Susceptibility to HLA-DM is determined by a dynamic conformation of major histocompatibility complex class II molecule bound with peptide
Yin L, et al., J Biol Chem, pii: jbc.M114.585539, 2014

  Design, Synthesis, and Biological Evaluation of Novel FAK Scaffold Inhibitors Targeting the FAK-VEGFR3 Protein-protein Interaction
Gogate PN, et al., Eur J Med Chem., 80C:154-166, 2014

  YlxM is a Newly Identified Accessory Protein that Influences Function of Signal Recognition Particle (SRP) Pathway Components in Streptococcus Mutans
Williams ML, et al., J Bacteriol, 196(11):2043-52, 2014

  Striatins Contain a Noncanonical Coiled Coil That Binds Protein Phosphatase 2A A Subunit to Form a 2:2 Heterotetrameric Core of Striatin-interacting Phosphatase and Kinase (STRIPAK) Complex
Chen C, et al., J Biol Chem, 289(14):9651-61, 2014

  Sensor Domain of Histidine Kinase KinB of Pseudomonas A HELIX-SWAPPED DIMER
Tan K, et al., J Biol Chem, 289(18):12232-44, 2014

  Bio-layer Interferometry for Measuring Kinetics of Protein-protein Interactions and Allosteric Ligand Effects
Shah NB and Duncan TM, J Vis Exp, (84):e51383, 2014

  Structure of MST2 SARAH Domain Provides Insights into Its Interaction with RAPL
Liu G, et al., J Struct Biol, 185(3):366-74, 2014

  Molecular Determinants of the Interaction Between Doa1 and Hse1 Involved in Endosomal Sorting
Han S, et al., Biochem Biophys Res Commun , 446(1):352-7, 2014

  DC-SIGN Plays a Stronger Role than DCIR in Mediating HIV-1 Capture and Transfer
Jin W, et al., Virology, 458-459:83-92, 2014

  Isolation of Dengue Virus-specific Memory B Cells with Live Virus Antigen from Human Subjects Following Natural Infection Reveals the Presence of Diverse Novel Functional Groups of Antibody Clones
Smith SA, et al., J Virol, pii: JVI.00247-14, 2014

  Global identification of CobB Interactors by an Escherichia Coli Proteome Microarray
Liu CX, et al., Acta Biochim Biophys Sin (Shanghai), 46(7):548-55, 2014

  Diversity of the Murine Antibody Response Targeting Influenza A (H1N1pdm09) Hemagglutinin
Wilson JR, et al., Virology, 458-459:114-24, 2014

  Ribosomal Protein S19 Binding Domain Provides Insights into Hantavirus Nucleocapsid Protein-mediated Translation Initiation Mechanism
Ganaie SS, et al., Biochem J, doi:10.1042/BJ20140449, 2014

  Antibody-based Prevention of von Willebrand Factor Degradation Mediated by Circulatory Assist Devices
Rauch A, et al., Thromb Haemost, 112(5), 2014

  The Sphingolipid Receptor S1PR2 is a Receptor for Nogo-A Repressing Synaptic Plasticity
Kempf A, et al., PLoS Biol, 12(1):e1001763, 2014

  The Carboxy-terminus of BAK1 Regulates Kinase Activity and is Required for Normal Growth of Arabidopsis
Oh MH, et al., Front Plant Sci, 5:16, 2014

  A Dynamin Homolog Promotes the Transition from Hemifusion to Content Mixing in Intracellular Membrane Fusion
Kulkarni A, et al., Traffic, 15(5):558-71, 2014

  Super Spy Variants Implicate Flexibility in Chaperone Action
Quan S, et al., Elife, 3:e01584, 2014

  Phosphorylation of Sli15 by Ipl1 Is Important for Proper CPC Localization and Chromosome Stability in Saccharomyces cerevisiae
Makrantoni V, et al., PLoS One, 9(2):e89399, 2014

  The Histone Chaperones Vps75 and Nap1 Form Ring-like, Tetrameric Structures in Solution
Bowman A, et al., Nucleic Acids Res, 42(9):6038-51, 2014

  FRET-based System for Probing Protein-protein Interactions between σR and RsrA from Streptomyces Coelicolor in Response to the Redox Environment
Wei ZH, et al., PLoS One, 9(3):e92330, 2014

  Improving the Anti-Toxin Abilities of the CMG2-Fc Fusion Protein with the Aid of Computational Design
Xi Y, et al., PLoS One, 9(8):e104674, 2014

2013

  Glycan-dependent and Independent Interactions Contribute to Cellular Substrate Recruitment by Calreticulin
Wijeyesakere S, Rizvi S and Raghavan M, J Biol Chem, 288(49), 35104-35116, 2013

  Targeting Nuclear Import Shuttles, Importins/Karyopherins Alpha by a Peptide Mimicking the NFκB1/p50 Nuclear Localization Sequence
Zienkiewicz J, Armitage A and Hawiger J, J Am Heart Assoc, 2(5):e000386, 2013

  MAIT Recognition of a Stimulatory Bacterial Antigen Bound to MR1
López-Sagaseta J, et al., J Immunol, 191(10), 5268-77, 2013

  Crystal Structure of the Hendra Virus Attachment G Glycoprotein Bound to a Potent Cross-reactive Neutralizing Human Monoclonal Antibody
Xu K, et al., PLoS Pathog, 9(10):e1003684, 2013

  Structure and Function of Norrin in Assembly and Activation of a Frizzled 4-Lrp5/6 Complex
Ke J, et al., Genes Dev, 27(21), 2305-19, 2013

  Signaling of High Mobility Group Box 1 (HMGB1) Through Toll-like Receptor 4 in Macrophages Requires CD14
Kim S, et al. , Molecular Medicine, 19, 88-98, 2013

  Intravenous Immunglobulin Binds Beta Amyloid and Modifies Its Aggregation, Neurotoxicity and Microglial Phagocytosis In Vitro
Cattepoel S, et al., PLoS One, 8(5):e63162, 2013

  Nck-mediated Recruitment of BCAP to the BCR Regulates the PI(3)K-Akt Pathway in B Cells
Castello A, et al., Nat Immunol, 14(9), 966-75, 2013

  Intrinsic Selectivity of Notch 1 for Delta-like 4 over Delta-like 1
Andrawes M, et al., J Biol Chem, 288(35), 25477-25489, 2013

  Disassembly of All SNARE Complexes by N-Ethylmaleimide-sensitive Factor (NSF) is Initiated by a Conserved 1:1 Interaction Between α-Soluble NSF Attachment Protein (SNAP) and SNARE Complex
Vivona S, et al., J Biol Chem, 288(34), 24984-91, 2013

  Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation
Yin Q, et al., Cell Rep, 4(2), 327-39, 2013

  pH-induced Quaternary Assembly of Vitreoscilla Hemoglobin: the Monomer Exhibits Better Peroxidase Activity
Li W, et al., Biochim Biophys Acta, 1834(10), 2124-2132, 2013

  Chemical Cross-linking of HIV-1 Env for Direct TLR7/8 Ligand Conjugation Compromises Recognition of Conserved Antigenic Determinants
Feng Y, et al., Virology, 446, 56-65, 2013

  Identify the Key Amino Acid of BAFF Binding with TACI
Wang R, et al., Cell Immunol, 284(1-2), 84-90, 2013

  The E3 Ubiquitin Ligase CHIP and the Molecular Chaperone Hsc70 Form a Dynamic, Tethered Complex
Smith M, et al., Biochemistry, 52(32), 5354-64, 2013

  Anti-HIV-1 Activity and Structure-activity-relationship Study of a Fucosylated Glycosaminoglycan from an Echinoderm by Targeting the Conserved CD4 Induced Epitope
Lian W, et al., Biochim Biophys Acta, 1830(10), 4681-91, 2013

  Disruption of Focal Adhesion Kinase and p53 Interaction with Small Molecule Compound R2 Reactivated p53 and Blocked Tumor Growth
Golubovskaya V, et al., BMC Cancer, 13(1), 342, 2013

  Monitoring the Kinetics of the pH Driven Transition of the Anthrax Toxin Prepore to the Pore by Biolayer Interferometry and Surface Plasmon Resonance
Naik S, et al., Biochemistry, 52, 6335-6347, 2013

  Effects on Peptide Binding Affinity for TNFα by PEGylation and Conjugation to Hyaluronic Acid
Elder A, et al., European Polymer Journal, 49, 2968-2975, 2013

  The Novel Human Beta-defensin 114 Regulates Lipopolysaccharide(LPS)-mediated Inflammation and Protects Sperm from Motility Loss
Yu, H, et al., J Biol Chem, 288(17), 12270-82, 2013

  Coagulation Factor X Shields Adenovirus Type 5 from Attack by Natural Antibodies and Complement
Xu, Z, et al., Nat Med, 19(4), 452-7, 2013

  ATP-competitive Inhibitors Block Protein Kinase Recruitment to the Hsp90-Cdc37 System
Polier, S, et al., Nat Chem Biol, 9(5), 307-12, 2013

  Structural Mechanism of CCM3 Heterodimerization with GCKIII Kinases
Zhang, M, et al., Structure, 21(4), 680-688, 2013

  Label-free Methods of Reporting Biomolecular Interactions by Optical Biosensors
Citartan, M, et al., Analyst, 138(13), 3576-3592, 2013

  Dynamin_SNARE Interactions Control Trans-SNARE Formation in Intracellular Membrane Fusion
Alpadi, K, et al., Nat Commun, 4, 1704, 2013

  14-3-3 Proteins Interact with a Hybrid Prenyl-Phosphorylation Motif to Inhibit G Proteins
Riou, P, et al., Cell, 153(3), 640-53, 2013

  The Molecular Basis for Mucosal-associated Invariant T cell Recognition of MR1 Proteins
Lopez-Sagaseta, J, et al., Proc Natl Acad Sci U S A, 110(19), E1771-8, 2013

  Structural Characterization of the Self-association of the Death Domain of p75NTR
Qu, Q, et al., PLoS One, 8(3):e57839, 2013

  F1-ATPase of Escherichia coli: The ε-inhibited State Forms After ATP Hydrolysis, is Distinct from the ADP-inhibited State, and Responds Dynamically to Catalytic-site Ligands
Shah, NB, et al., J Biol Chem, 288(13), 9383-95 , 2013

  The Regulation of Apoptosis by the Downstream Regulatory Element Antagonist Modulator/Potassium Channel Interacting Protein 3 (DREAM/KChIP3) Through Interactions with Hexokinase I
Craig, T A, et al., Biochem Biophys Res Commun, 433(4), 508-12, 2013

  Structure of a Classical Broadly Neutralizing Stem Antibody in Complex with a Pandemic H2 Influenza Virus Hemagglutinin
Dreyfus C, Ekiert D C, Wilson I A, J Virol, 87(12), 7149-54 , 2013

  Engineering HIV Envelope Protein to Activate Germline B Cell Receptors of Broadly Neutralizing Anti-CD4 Binding Site Antibodies
McGuire, A T, et al. , J Exp Med, 210(4), 655-663, 2013

  Structure of the MST4 in Complex with MO25 Provides Insights into its Activation Mechanism
Shi, Z, et al., Structure, 21(3), 449-61, 2013

  Selection of a High-affinity WW Domain Against the Extracellular Region of VEGF Receptor Isoform-2 from a Combinatorial Library using CIS Display
Patel, S, et al., Protein Eng Des Sel, 26(4), 307-15 , 2013

  β-Arrestin-1 Directly Interacts with Gαs and Regulates its Function
Li, B, et al., FEBS Lett, 587(5), 410-6, 2013

  Conformational Biosensors Reveal GPCR Signalling from Endosomes
Irannejad, R, et al., Nature, 495(7442), 534-8, 2013

  Structural Insights into the Regulation of Cohesion Establishment by Wpl1
Chatterjee, A, et al., EMBO J , 32(5), 677-87, 2013

  N332-Directed Broadly Neutralizing Antibodies Use Diverse Modes of HIV-1 Recognition: Inferences from Heavy-Light Chain Complementation of Function
Pancera, M, et al., PLoS One, 8(2):e55701, 2013

  Structural Plasticity of Histones H3-H4 Facilitates Their Allosteric Exchange Between RbAp48 and ASF1
Zhang, W, et al., Nat Struct Mol Biol, 20(1), 29-35, 2013

  HLA-DO Acts as a Substrate Mimic to Inhibit HLA-DM by a Competitive Mechanism
Guce, A I, et al., Nat Struct Mol Biol, 20(1), 90-8, 2013

2012

  Evaluation of Taylor Dispersion Injections: Determining Kinetic/Affinity Interaction Constants and Diffusion Coefficients in Label-Free Biosensing
Quinn JG, Anal biochem, 421: 401-410, 2012

  Modeling Taylor Dispersion Injections: Determination of Kinetic/Affinity Interaction Constants and Diffusion Coefficients in Label-Free Biosensing
Quinn JG, Anal biochem, 421: 391-401, 2012

  Identification of the Key Functional Domain of BAFF for Binding TACI by Computer-Guided Molecular Modeling Method
Wang, R., et al., J Genet Syndr Gene Ther , 3 (114). doi:10.4172/2157-7412.1000114, 2012

  Endoglin Requirement for BMP9 Signaling in Endothelial Cells Reveals New Mechanism of Action for Selective Anti-Endoglin Antibodies
Nolan-Stevaux, O., et al., PloS One, 7(12):e50920, 2012

  Protein Microarrays, Biosensors, and Cell-based Methods for Secretome-wide Extracellular Protein-Protein Interaction Mapping
Gonzales, L.C. , Methods, 57(4), 448-58, 2012

  4F Decreases IRF5 Expression and Activation in Hearts of Tight Skin Mice
Xu, H., et al., PLoS One, 7(12):e52046, 2012

  IL-13-induced Airway Mucus Production is Attenuated by MAPK13 Inhibition
Alevy, Y. G., et al., J Clin Invest, 122(12), 4555-68, 2012

  Structural Mechanism of ER Retrieval of MHC Class I by Cowpox
McCoy, W. H., et al., PLoS Biol, 10(11):e1001432, 2012

  Furin-cleaved Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Is Active and Modulates Low Density Lipoprotein Receptor and Serum Cholesterol Levels
Lipari, M.T., et al., J Biol Chem, 287(52), 43482-91, 2012

  Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus Anthracis Spores
RN Kirchdoerfer, et al., Structure, 20(3), 479-486, 2012

  Identification of Galectin-1 and Galectin-3 as Novel Partners for Von Willebrand Factor
N Saint-Lu, et al., Arterioscler Thromb Vasc Biol, 32(4), 894-901, 2012

  Determination of Cathepsin S Abundance and Activity in Human Plasma and Implications for Clinical Investigation
J.M. Cox, et al., Analytical Biochemistry, 430(2), 130-137, 2012

  The Sclerostin-bone Protein Interactome
Devarajan-Ketha, H., et al., Biochemical and Biophysical Research Communications, 417 (2), 830-835, 2012

  Chemical and Genetic Evidence for the Involvement of Wnt Antagonist Dickkopf2 in Regulation of Glucose Metabolism
Li, X., et al., Proc Natl Acad Sci USA, 109(28), 11402-7, 2012

  Bifunctional CD4-DC-SIGN Fusion Proteins Demonstrate Enhanced Avidity to gp120 and Inhibit HIV-1 Infection and Dissemination
Du, T., et al., Antimicrobial Agents and Chemotherapy, 56(9), 4640-9, 2012

  Factor VIII and von Willebrand Factor are Ligands for the Carbohydrate-Receptor Siglec-5
Pegon, J.N., et al., Haematologica, 97(12), 1855-63, 2012

  Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING
Yin, Q., et al., Molecular Cell, 46 (6), 735-745, 2012

  Optimization of Affinity, Specificity and Function of Designed Influenza Inhibitors Using Deep Sequencing
Whitehead, T.A., et al., Nature Biotechnology, 30(6), 543-548, 2012

  Helicobacter Pylori Hydrogenase Accessory Protein HypA and Urease Accessory Protein UreG Compete with Each Other for UreE Recognition
Benoit, S.L., et al., Biochimica et Biophysica Acta (BBA), 1820 (10), 1519-1525, 2012

  Differential Polyubiquitin Recognition by Tandem Ubiquitin Binding Domains of Rabex-5
Shin, D., et al., Biochem Biophys Res Commun, 423(4), 757-62, 2012

  Domain Activities of PapC Usher Reveal the Mechanism of Action of an Escherichia coli Molecular Machine
Volkan, E, et al., Proc Natl Acad Sci USA, 109 (24), 9563-9568, 2012

  p53/HMGB1 Complexes Regulate Autophagy and Apoptosis
Livesey, K.M., et al., Cancer Research, 72(8), 1996-2005, 2012

  Structure of Bradavidin - C-Terminal Residues Act as Intrinsic Ligands
Leppiniemi, J., et al., PLoS ONE, 7(5), e35962, 2012

  Secretion of the Housekeeping Protein Glyceraldehyde-3-phosphate Dehydrogenase by the LEE-encoded Type III Secretion System in Enteropathogenic Escherichia coli
Aguilera, L., et al., Int J Biochem Cell Biol, 44(6), 955-962, 2012

  Enzyme Kinetics and Interaction Studies for Human JNK1[beta]1 and Substrates ATF2 And cJun
Figuera-Losada, M.; LoGrasso, P.V., J Biological Chemistry, 287(16), 13291-13302, 2012

  Heterosubtypic Antibody Recognition of the Influenza Virus Hemagglutinin Receptor Binding Site Enhanced by Avidity
P.S. Lee, et al., Proc Natl Acad Sci USA, 109(42), 17040-5, 2012

  Self-antigen Recognition by Follicular Lymphoma B Cell Receptors
K.L. Sachen, et al. , Blood, 120(20), 4182-90, 2012

  Structural Insights into SUN-KASH Complexes Across the Nuclear Envelope
W. Wang, et al., Cell Research, 22(10), 1440-1452, 2012

  Changes in the Oligomerization Potential of the Division Inhibitor UgtP Co-ordinate Bacillus Subtilis Cell Size with Nutrient Availability
A.C. Chien, et al., Molecular Microbiology, 86(3), 594-610, 2012

  Existence of Separate Domains in Lysin PlyG for Recognizing Bacillus anthracis Spores and Vegetative Cells
H. Yang, et al., Antimicrob Agents Chemother, 56(10), 5031-5039, 2012

  Do GGA Adaptors Bind Internal DXXLL Motifs?
B. Doray, et al., Traffic, 13(10), 1315-1325, 2012

  MAP Kinases Bind Endothelial Nitric Oxide Synthase
Chrestensen, C.A., McMurry, J.L., Salerno, J.C., FEBS Open Bio, 2, 51-55 , 2012

  Mapping the HLA-DO/HLA-DM Complex by FRET and Mutagenesis
Yoon T, et al., Proc Natl Acad Sci USA, 109(28), 11276-81, 2012

2011

  Identification of Conformational Core Epitope Lys68 in C5a Based on the 3-D Modeling Complex C5a and its Functional Antibody F20
Wei, H., et al., Molecular Immunology, 48(12-13), 1377-1383, 2011

  Divergent Activities Of Osteogenic BMP2, And Tenogenic BMP12 And BMP13 Independent Of Receptor Binding Affinities
Berasi, S.P., et al., Growth Factors, 29(4), 128-139, 2011

  Recognition of Ubch5c and the Nucleosome by the Bmi1/Ring1b Ubiquitin Ligase Complex
Bentley, M.L., et al., The EMBO Journal, 30(16), 3285-3297, 2011

  Inhibitors of Androgen Receptor Activation Function-2 (AF2) Site Identified through Virtual Screening
Axerio-Cilies, P., et al., Journal of Medicinal Chemistry, 54 (18), 6197-6205, 2011

  The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM) Mutually Exclusive Binding of Cofactors to the N-Terminal Domain of P97
Hanzelmann, P. and Schindelin, H., Journal of Biological Chemistry, 286(44), 38679-38690, 2011

  Characterization of Crude Echis Carinatus Venom-induced Cytotoxicity in HEK 293T Cells
Pierce, R.D., et al., Journal of Venom Research, 2, 59-67, 2011

  Impact of Gene Vector Design on the Control of Recombinant Monoclonal Antibody Production by Chinese Hamster Ovary Cells
Davies, S.L., et al., Biotechnology Progress, 27 (6), 1689-1699, 2011

  TMEFF2 is a PDGF-AA Binding Protein with Methylation-Associated Gene Silencing in Multiple Cancer Types Including Glioma
Lin, K., et al., PLoS ONE, 6(4), e18608, 2011

  The Peroxisomal Targeting Signal 1 in Sterol Carrier Protein 2 is Autonomous and Essential for Receptor Recognition
Williams, C.P., et al. , BMC Biochemistry, 12, 12, 2011

  Chaperone Activity of alpha β-Crystallin Is Responsible for Its Incorrect Assignment as an Autoantigen in Multiple Sclerosis
Rothbard, J.B., et al., J Immunology, 186(7), 4263-4268, 2011

  Rate, Affinity and Calcium Dependence of Nitric Oxide Synthase Isoform Binding to the Primary Physiological Regulator Calmodulin
McMurry, J.L, et al. , FEBS Journal, 278(24) 4943-4954, 2011

  Robo4 Maintains Vessel Integrity And Inhibits Angiogenesis By Interacting With UNC5B
Koch, A.W., et al., Developmental Cell, 20(1), 33-46, 2011

  Wnt Antagonists Bind through a Short Peptide to the First β-Propeller Domain of LRP5/6
Bourhis, E., et al., Structure, 19 (10), 1433-1442, 2011

  In Vitro Analyses of the Dysregulated R206H ALK2 Kinase-FKBP12 Interaction Associated with Heterotopic Ossification in FOP
Groppe, J.C., et al., Cells Tissues Organs, 194 (2-4), 291-295 , 2011

  Functional Importance of BAK1 Tyrosine Phosphorylation In Vivo
Oh, M.H., et al., Plant Signaling and Behavior, 6 (3), 400-405, 2011

2010

  Specificity for Human Hemoglobin Enhances Staphylococcus aureus Infection
Pischany, G., et al., Cell Host Microbe, 8, 544-550, 2010

  Allosteric Peptide Activators of Pro-Hepatocyte Growth Factor Stimulate Met Signaling
Landgraf, K.E., et al., J Biological Chemistry, 285, 40362-40372, 2010

  Wnt Isoform-Specific Interactions with Coreceptor Specify Inhibition or Potentiation of Signaling by LRP6 Antibodies
Gong, Y., et al., PLoS ONE, 5(9), e12682, 2010

  Structural Bases for the Interaction of Frataxin with the Central Components of Iron-Sulphur Cluster Assembly
Prischi, F., et al., Nature Communications, 1, 95, 2010

  Kinetic Characterization of Salmonella FliK-FlhB Interactions Demonstrates Complexity of the Type III Secretion Substrate-Specificity Switch
Morris, D.P., et al., Biochemistry, 49(30), 6386-6393, 2010

  Hedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-Active Site
Maun, H.R., et al., J Biological Chemistry, 285(34), 26570-26580, 2010

  Reconstitution of a Frizzled8-Wnt3a-LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6
Bourhis, E., et al., Journal of Biological Chemistry, 285 (12), 9172-9179, 2010

  Molecular Mechanism of the Synaptotagmin-SNARE Interaction in Ca2+-Triggered Vesicle Fusion
Vrljic, M., et al., Nature Structural and Molecular Biology, 17(3), 325-331, 2010

  Direct Transactivator-Transcription Factor IID (TFIID) Contacts Drive Yeast Ribosomal Protein Gene Transcription
Layer, J.H., et al., J Biological Chemistry, 285(20), 15489-15499, 2010

  Generation of Stable Cell Clones Expressing Mixtures of Human Antibodies
de Kruif, J., et al., Biotechnology and Bioengineering, 106 (5), 741-750, 2010

  Autophosphorylation of Tyr-610 in the Receptor Kinase BAK1 Plays a Role in Brassinosteroid Signaling and Basal Defense Gene Expression
Oh, M.h., et al., Proc Nat Acad Sci USA, 107(41), 17827-17832, 2010

2009

  The Structure of SHH in Complex with HHIP Reveals a Recognition Role for the Shh Pseudo Active Site in Signaling
Bosanac, I., et al., Nature Structural & Molecular Biology, 16(7), 691-697, 2009

  Structural Basis for Parathyroid Hormone-Related Protein Binding to the Parathyroid Hormone Receptor and Design of Conformation-Selective Peptides
Pioszak, A.A., et al., J Biological Chemistry, 284(41), 28382-28391, 2009

  Poxvirus Proteomics and Virus-Host Protein Interactions
Van Vliet, K., et al., Microbiol Mol Biol Rev, 73(4), 730-749, 2009

  Structure of IL-33 and Its Interaction with the ST2 and IL-1RAcP Receptors - Insight into Heterotrimeric IL-1 Signaling Complexes
Lingel, A., et al., Structure, 17(10), 1398-1410, 2009

2008

  The Surface Protein TIGIT Suppresses T Cell Activation by Promoting the Generation of Mature Immunoregulatory Dendritic Cells
Yu, X., et al., Nature Immunology, 10(1), 48-57, 2008

2005

  Cleavage-Independent HIV-1 Env Trimers Engineered as Soluble Native Spike Mimetics for Vaccine Design,2015,Target Identification,Protein-Protein Interactions,Vaccines,,Cell Rep,"Sharma S
native flexibly linked, 2005

Documents Found

Probing Structurally Altered and Aggregated States of Therapeutically Relevant Proteins Using a GroEL-Biosensor Coupled to Bio-layer Interferometry

  Probing Structurally Altered and Aggregated States of Therapeutically Relevant Proteins Using a GroEL-Biosensor Coupled to Bio-layer Interferometry

Octet Biolayer Interferometery: An Efficient Method to Detect Modular Transient Protein-Protein Interactions

  Octet Biolayer Interferometery: An Efficient Method to Detect Modular Transient Protein-Protein Interactions

AN 14: Biomolecular Binding Kinetics Assays on the Octet Platform

  AN 14: Biomolecular Binding Kinetics Assays on the Octet Platform

Characterisation of Novel Lipid-Protein Interactions Using Biolayer Interferometry

  Characterisation of Novel Lipid-Protein Interactions Using Biolayer Interferometry

Kinetics on the Octet Systems: What Lies Beneath the Curves

  Kinetics on the Octet Systems: What Lies Beneath the Curves

Use of Chaperone Proteins and Octet Bio-Layer Interferometry to Detect Protein Folding/Unfolding Events in a High-Throughput Format

  Use of Chaperone Proteins and Octet Bio-Layer Interferometry to Detect Protein Folding/Unfolding Events in a High-Throughput Format

AN 9: CaptureSelect Affinity Ligands for Antibody Detection and Characterization

  AN 9: CaptureSelect Affinity Ligands for Antibody Detection and Characterization

AN 8: Optimizing Protein-Protein and Protein-Small Molecule Kinetics Assays

  AN 8: Optimizing Protein-Protein and Protein-Small Molecule Kinetics Assays

Poster: BLI as a Platform for Detect Protein Misfolding Using the GroEL Chaperonin

  Poster: BLI as a Platform for Detect Protein Misfolding Using the GroEL Chaperonin

Octet HT Screen of Protein Aggregates for Crystallization

  Octet HT Screen of Protein Aggregates for Crystallization

Structural Basis of Sonic Hedgehog Regulation by Neutralizing Antibody 5E1 and Hedgehog-Interacting Protein: Role of the Sonic Hedgehog Pseudo-Active Site in Signaling

  Structural Basis of Sonic Hedgehog Regulation by Neutralizing Antibody 5E1 and Hedgehog-Interacting Protein: Role of the Sonic Hedgehog Pseudo-Active Site in Signaling

AN 2: Convert an ELISA Assay into an Octet Quantitation Assay

  AN 2: Convert an ELISA Assay into an Octet Quantitation Assay