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High throughput antibody discovery at the Vanderbilt Vaccine Center

High throughput antibody discovery at the Vanderbilt Vaccine Center

Vanderbilt Vaccine Center – Nashville, TN

Robert Carnahan, PhD, Associate Professor

Octet HTX system

The Challenge

The Vanderbilt Vaccine Center is working to develop and test new vaccine for infections diseases through next generation antibody science. In identifying lead candidates, the Center must move from large panels of antibodies to advance a smaller, more manageable number for further investigation. As an academic hub collaborating with researchers around the world on infectious diseases caused by a myriad of viruses and bacteria, the Center also needs flexible analytical platforms that can be adapted to assay needs as well as an easy-to-use design that enables new users to quickly gain comfort with.

The Solution

The Vanderbilt Vaccine Center became one of the first academic institutes in North America to adopt the Octet HTX system. The Octet HTX system provides the capacity to screen large panels of antibodies in parallel and is designed for users to quickly learn, develop assays for, and generate data.

“The time to generate data is extremely fast. Within a week of being installed, the lab had already generated two large data sets” - Robert Carnahan, Ph.D., Associate Professor at Vanderbilt.

Products Used

The Octet HTX System offer label-free molecular interaction analysts with state-of-the-art high throughput platforms that facilitate the rapid characterization and development of biologics drug molecules.

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