Anti-CHO HCP Detection Kit

For CHO Host Cell Protein Detection

  • Completely hands-off, walk-away HCP analysis
  • Fully analyzed HCP results for 96 samples in one hour
  • High precision assays with 5-10% CVs
  • Detection sensitivity as low as 0.5 ng/mL

Dip and Read Anti-CHO HCP Detection Kit

Host cell proteins (HCPs) are contaminants found in biopharmaceuticals expressed in bacterial, yeast or mammalian production cell lines. Among protein expression cell lines, Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for industrial production of recombinant protein therapeutics. However, manufacturing and production processes of biopharmaceuticals often leave behind contaminating HCPs from CHO cells. These residual HCPs carry substantial risk of decreasing efficacy of the drug and causing adverse immunogenic reactions in patients. Hence, detecting residual HCP contaminants and methods to reduce them to the lowest acceptable levels are critical aspects of drug safety and qualification.

ForteBio LLC and Cygnus Technologies have jointly developed the Anti-CHO HCP Detection Kit for quantitation of residual HCPs. The Octet® platform's rapid high throughput protein analysis combined with the broad HCP recognition and sensitivity of the industry-standard Cygnus 3G anti-CHO HCP antibody bring scientists the best of both worlds for HCP analysis.

Resources of Anti-CHO HCP Detection Kit

Data Sheet Dip and Read™ Anti-CHO HCP Detection Kit

Host cell proteins (HCPs) are contaminants found in biopharmaceuticals expressed in bacterial, yeast or mammalian production cell lines. Among protein expression cell lines, Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for industrial production of recombinant protein therapeutics. However, manufacturing and production processes of biopharmaceuticals often leave behind contaminating HCPs from CHO cells.

Read more

Data Sheet Ready BLI Detection Kit – Residual Protein A

Detecting and minimizing Protein A contamination is a critical quality control step in antibody therapeutic development and production. The Ready BLI Detection kit - Residual Protein A from Pall ForteBio applies the principles of BLI to enable sensitive, accurate quantitation of leached Protein A in bioprocess samples while maintaining a simple workflow. The kit utilizes a validated sample treatment method for dissociating Protein A from antibodies that does not require boiling, neutralization, or centrifugation steps.

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Flyer BLI Biosensors Selection Guide

Read this document which is helpful in the selection of Biosensor with their detail information.

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Scientific Poster Cygnus Anti-CHO HCP Detection Kit for Fast and Easy Detection of Residual CHO Host Cell Proteins on Octet Systems

Host cell proteins (HCPs) are contaminants found in biopharmaceuticals expressed in bacterial, yeast or mammalian production cell lines. Among protein expression cell lines, Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for industrial production of recombinant protein therapeutics.

Read more

Technical Guide CHO Host Cell Protein Detection

Host cell proteins (HCPs) are contaminants found in biopharmaceuticals expressed in bacterial, yeast or mammalian production cell lines. Among protein expression cell lines, Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for industrial production of recombinant protein therapeutics

Read more

Technical Guide Host Cell Protein Detection

Host cell proteins (HCPs) are contaminants found in biopharmaceuticals that originate from the production cell lines of bacterial, yeast or mammalian cell culture. HCPs can reduce drug efficacy and delay or kill promising drug candidates through adverse patient reactions.

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Product Part Number
Anti-CHO HCP Detection Kit #18-5081
Anti-CHO HCP Detection Kit - Pack #18-5123

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