Anti-Murine IgG Quantitation (AMQ) Biosensors

For Determination of Antibody Concentration

  • Direct measurement of immunoglobulins (IgG) from mouse and rat species
  • Convenient working range 1–100 µg/mL
  • Assay samples without serially diluting or centrifugation
  • Assay mouse sera, cell lysates or supernatants
  • Fast turnaround of results

Anti-Murine IgG Quantitation (AMQ) Biosensors

ForteBio's Anti-Murine IgG Quantitation biosensors provide a rapid method for precise quantitation of murine immunoglobulins from crude lysates and cell culture supernatants. Factory immobilization of an anti-murine IgG (Fv) antibody to the biosensor surface enables direct detection of murine IgG analytes with minimal sample handling and facilitates sample quantitation from cell culture screening through downstream purification development.

Resources of Anti-Murine IgG Quantitation (AMQ) Biosensors

Application Note Fast Quantitation of Proteins and Antibodies Using the BLItz System

Traditional techniques for determining concentration of a target protein such as ELISA and HPLC are both elaborate and timeconsuming, especially when analyzing complex matrices. For bioprocess development and production applications, the use of more rapid protein analysis techniques enables timely, informed process decisions.

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Application Note MAb Quantitation: Protein A HPLC vs. Protein A Bio-layer Interferometry

There are currently 30 monoclonal antibodies approved by the FDA as biotherapeutic agents, representing the most rapidly growing class of new drugs. Despite advances in downstream processing technology, affinity purification of monoclonal antibodies using Protein A chromatography is still the industry standard. In order to use Protein A resin as productively as possible it is important to load the resin at close to its dynamic binding capacity (DBC)

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Application Note Biomolecular Binding Kinetics Assays on the Octet Platform

Direct measurement of biomolecular interactions plays an important role in biotherapeutic drug discovery and development. Label-Free analytical technologies such as the Octet® platform from Pall ForteBio provide a powerful means to obtain accurate information about rate of biomolecular complex formation and complex stability, key components of a drug-target interaction.

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Application Note Robust Quantitation Assay for Monoclonal Antibodies and Other Proteins on Octet Platform

The Octet platform provides analytical methods for measuring antibody and protein concentrations and binding affinities through various stages of drug discovery and development (Table 1). Octet systems circumvent many limitations of ELISA and HPLC assays, enabling informed decisions to be made earlier in both drug and process development – particularly when chromatography and other critical separation steps are needed.

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Data Sheet Anti-Murine IgG Biosensors

ForteBio’s Anti-Murine IgG Biosensors, in conjunction with the Octet System, are designed for monitoring antibody concentrations in mouse or rat sera and cell culture supernatants. Using Anti-Murine IgG Biosensors, the Octet System supports applications from assay development, clonal selection, and cell culture screening to concentration monitoring during development and manufacturing.

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Flyer BLI Biosensors Selection Guide

Read this document which is helpful in the selection of Biosensor with their detail information.

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Product Part Number
Biosensor / Anti-Murine IgG Quantitation (AMQ) Case #18-5024
Biosensor / Anti-Murine IgG Quantitation (AMQ) Pack #18-5023
Biosensor / Anti-Murine IgG Quantitation (AMQ) Tray #18-5022

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