CDH Biosensor

This CDH biosensor is a high capacity three-dimensional chemistry that uses a medium length Dextran hydrogel spacer with carboxylic acids

CDH Biosensor

(Replaces COOHV) This CDH biosensor is a high capacity three-dimensional chemistry that uses a medium length Dextran hydrogel spacer with carboxylic acids. This biosensor contains a high number of carboxylic acid functional groups that allows a large amount of target to be coupled onto the surface. This is particularly useful to observe the interactions of small molecules or for target that exhibit low binding activity. Amine coupling is the standard immobilization method for CDH. Its coupling capacity is the higher than the CDL biosensors.

Resources of CDH Biosensor

Application Note Commitment to Covalency : Kinetics of Irreversible Inhibitors on the Pioneer FE System

The principal role of assay groups in drug discovery is to provide reliable methods, analysis, and data for confident decision-making about series progression. Particular assays are chosen to differentiate between affinity, specificity, cellular action, and most important mechanism of action.

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Application Note Fragment Based Drug Discovery on Pioneer Systems Using Next Generation SPR Analysis

Fragment-based drug design (FBDD) has become an increasingly popular platform for the identification of lead candidates in drug discovery programs. The detection and characterization of fragment binding events is facilitated by sensitive biophysical technologies capable of detecting low-affinity interactions of low molecular weight compounds. Over the last decade approaches such as nuclear magnetic resonance (NMR), X-ray crystallography, differential scanning fluorimetry (DSF), and surface plasmon resonance (SPR) have become core technologies in many pharma

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Application Note Biomolecular Binding Kinetics Assays on the Octet Platform

Direct measurement of biomolecular interactions plays an important role in biotherapeutic drug discovery and development. Label-Free analytical technologies such as the Octet® platform from Pall ForteBio provide a powerful means to obtain accurate information about rate of biomolecular complex formation and complex stability, key components of a drug-target interaction.

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Flyer SPR biosensor selection guide – Pioneer Systems

Read this document which is helpful in the selection of SPR Biosensor with their detail information.

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Flyer BLI Biosensors Selection Guide

Read this document which is helpful in the selection of Biosensor with their detail information.

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Technical Guide Guidelines for OneStep Protocol Design

The Pioneer and Pioneer FE Next Generation SPR systems by ForteBio employ an innovative gradient injection technology based on Taylor dispersion called OneStep®. A OneStep injection produces a sigmoidal concentration gradient of analyte from a single sample vial by dispersing the sample through a buffer-filled capillary line that flows into the SPR flow cell.

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Product Part Number
Pioneer Biosensors – CDH #19-0128

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