HisCap Biosensor

The HisCap biosensor is based on a three-dimensional non-dextran hydrogel chemistry

HisCap Biosensor

The HisCap biosensor is based on a three-dimensional non-dextran hydrogel chemistry. It is modified with Nitrilotriacetic acid (NTA) functional groups that chelate Nickel ions for the selective capture of 6X and 10X His-tagged targets. This surface can be partially regenerated by injecting Imidazole, EDTA or other similar reagents that compete for Nickel. Typical uses are small molecule or peptide kinetics with His-tagged protein targets. COOH1

Resources of HisCap Biosensor

Application Note Biomolecular Binding Kinetics Assays on the Octet Platform

Direct measurement of biomolecular interactions plays an important role in biotherapeutic drug discovery and development. Label-Free analytical technologies such as the Octet® platform from Pall ForteBio provide a powerful means to obtain accurate information about rate of biomolecular complex formation and complex stability, key components of a drug-target interaction.

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Flyer SPR biosensor selection guide – Pioneer Systems

Read this document which is helpful in the selection of SPR Biosensor with their detail information.

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Flyer BLI Biosensors Selection Guide

Read this document which is helpful in the selection of Biosensor with their detail information.

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Technical Guide Guidelines for OneStep Protocol Design

The Pioneer and Pioneer FE Next Generation SPR systems by ForteBio employ an innovative gradient injection technology based on Taylor dispersion called OneStep®. A OneStep injection produces a sigmoidal concentration gradient of analyte from a single sample vial by dispersing the sample through a buffer-filled capillary line that flows into the SPR flow cell.

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Product Part Number
Pioneer Biosensors – HisCap #PS05AFB

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