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Label-free technologies for accurate determination of affinity and kinetics rate constants

From target molecule identification to lead selection and optimization, equilibrium affinity and kinetics rate constants are critical parameters in the advancement of potential therapeutic drug…

Octet Systems: Modernize biopharmaceutical QC testing to increase efficiency

Quality control of biological products to support clinical trials and post market assay activities require the evaluation of multiple critical product attributes.

Applying label-free insights to decipher CRISPR/Cas mechanisms and workflows

The discovery of the prokaryotic adoptive immunity machinery CRISPR/Cas technology in the last decade has revolutionized our capabilities in manipulating genetic information, providing a powerful…

Octet Bio-Layer Interferometry systems: Advancing development of coronavirus vaccine and therapeutics

Millions of people have been infected worldwide with the virus, and hundreds of thousands of deaths reported so far. The rapidly evolving epidemiology of the pandemic and absence of a licensed…

Identification of human neutralizing antibodies against MERS_CoV and their role in virus adaptive evolution

Tang XC, et al., 111(19):E2018-26., Proc Natl Acad Sci U S A., May 2014 In this report, the authors screened a human Ab-phage library using a novel panning strategy to identify seven neutralizing…

Evaluation of candidate vaccine approaches for MERS-CoV

Wang L, et al., 28;6:7712, Nature Communications, July 2015 The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) as a cause of severe respiratory disease highlights the need for…

Identification of a novel inhibitor against middle east respiratory syndrome Coronavirus Viruses

Sun Y, et al., 9(9). pii: E255, Viruses Sept. 2017 The Middle East respiratory syndrome coronavirus (MERS-CoV) was first isolated in 2012, and circulated worldwide with high mortality. The continual…

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