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Towards a solution to MERS_protective human mAb targeting different domains and functions of the MERS-coronavirus spike glycoprotein

Ivy Widjaja, et al., 8(1): 516–530., Emerging Microbes and Infections 2019 The Middle-East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus that causes severe and often fatal…


Structural basis for human coronavirus attachment to sialic acid receptors

M. Alejandra Tortorici, et al.,  26, pages481–489, Nature Structural & Molecular Biology 2019 Read More


Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein

Haixia Zhou, et al., 10, Article number: 3068, Nature Communications 2019 Most neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) target the receptor-binding…


An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections

Dang HV et al., 26(10):980-987, Nat Struct Mol Biol. Oct. 2019 Read More


A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV

Meng Yuan, et al., March 2020 The outbreak of COVID-19, which is caused by SARS-CoV-2 virus, continues to spread globally, but there is currently very little understanding of the epitopes on the…


Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

Alexandra C. Walls, et al, pii: S0092-8674(20)30262-2 Cell March 2020 Read More


A Cryptic Site of Vulnerability on the Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein

M. Gordon Joyce, et al, March 2020 SARS-CoV-2 is a zoonotic virus that has caused a pandemic of severe respiratory disease—COVID-19— within several months of its initial identification. Comparable…


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