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Fab-Arm Exchange Combined with Selective Protein A Purification Results in a Platform for Rapid Preparation of Monovalent Bispecific Antibodies Directly from Culture Media

Fab-Arm Exchange Combined with Selective Protein A Purification Results in a Platform for Rapid Preparation of Monovalent Bispecific Antibodies Directly from Culture Media


Certificates of Analysis

Our online CoA search allows easier access to the most up to date certificates for our customers, and makes things more environmentally friendly for all of us. To view your CoA, select the product…


Peptides of Presenilin-1 Bind the Amyloid Precursor Protein Ectodomain and Offer a Novel and Specific Therapeutic Approach to Reduce β-Amyloid in Alzheimer's Disease

  Dewji N, et al., 10(4):e0122451, PLoS One, 2015 Accumulation of β-Amyloid (Aβ) in the brain is believed to be the initiator of Alzheimer's disease (AD). This study demonstrates that two…


Octet Potency Assay: Development, Qualification and Validation Strategies

In this application note, we discuss the strategies for the development and validation of a potency assay using Octet® systems. We have highlighted the Octet system’s ease-ofuse and fast time to…


Customized quantitation of recombinant therapeutic proteins using High Precision Streptavidin biosensors (SAX)

The accurate determination of recombinant protein titer is critical to the selection of high-producing clones during cell line development and in optimization of bioreactor conditions during…


Analysis of FcRn-Antibody Interactions on the Octet Platform

The Fc region of human IgG contributes to a number of beneficial biological and pharmacological characteristics of therapeutic antibodies.


Analysis of Fc-gamma Receptor-IgG Interactions on the Octet Platform

Fc gamma receptors (FcγRs) are membrane glycoproteins with affinity for the Fc region of immunoglobulin G (IgG). FcγRs expressed on the surface of immune effector cells play a key role in initiating…


A Protein Engineering of Bacillus Thuringiensis δ-Endotoxin by Conjugating with 4"-O-succinoyl Abamectin

Pan Z, et al., 62, 211-6, Int J Biol Macromol, 2013 In this study, Bt toxin was conjugated with 4-O-succinoyl abamectin to construct a new biocide (BtA). The Octet RED system was used to investigate…


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